Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death-allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons.
Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00024 | GMF beta/GMFB Protein, Human, Recombinant (His)
GMF beta/GMFB Protein, Human, Recombinant (His)
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Human | E. coli |
Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor... | |||
TMPJ-00081 | CNTF Protein, Human, Recombinant
CNTF Protein, Human, Recombinant
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Human | E. coli |
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor ax... | |||
TMPJ-00086 | CT-1 Protein, Human, Recombinant (His)
CT-1 Protein, Human, Recombinant (His)
|
Human | E. coli |
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate ... | |||
TMPJ-00100 | Artemin Protein, Human, Recombinant
Artemin Protein, Human, Recombinant
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Human | E. coli |
Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a varia... | |||
TMPJ-00124 | TNF alpha Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His)
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Human | E. coli |
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16 KDa and t... | |||
TMPJ-00125 | TNF alpha Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His)
|
Human | E. coli |
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and t... | |||
TMPJ-00134 | Pro-BDNF Protein, Human, Recombinant
pro-BDNF Protein, Human, Recombinant
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Human | E. coli |
The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-con... | |||
TMPJ-00250 | LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-te... | |||
TMPJ-00255 | TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
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Human | HEK293 Cells |
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and... | |||
TMPJ-00256 | Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weig... | |||
TMPJ-00259 | TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
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Human | HEK293 Cells |
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and... | |||
TMPJ-00260 | Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weig... | |||
TMPJ-00622 | Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 ... | |||
TMPJ-00771 | TGF beta 1 Protein, Mouse/Rat, Recombinant
TGF beta 1 Protein, Mouse/Rat, Recombinant
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Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular... | |||
TMPJ-00772 | Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | HEK293 Cells |
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weig... | |||
TMPJ-01414 | GDF-15 Protein, Mouse, Recombinant (His & Flag)
GDF-15 Protein, Mouse, Recombinant (His & Flag)
|
Mouse | HEK293 Cells |
Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be ... | |||
TMPK-00109 | Artemin Protein, Human, Recombinant (hFc)
Artemin Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor ... | |||
TMPK-00119 | TNF alpha Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the acces... | |||
TMPK-00120 | TNF alpha Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the a... | |||
TMPK-00121 | TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3... |