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Neurotrophins

Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death-allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons.

Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis.

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Species
Canine (6)
Cynomolgus (10)
Ferret (2)
Human (56)
Mouse (25)
Rabbit (1)
Rat (10)
Rhesus (4)
Expression System
Baculovirus Insect Cells (1)
CHO Cells (3)
E. coli (34)
HEK293 Cells (63)
P. pastoris (Yeast) (1)
Tag
C-6xHis (2)
C-His (20)
C-His-Avi (3)
C-hFc (3)
N-6xHis (3)
N-6xHis-Avi (1)
N-8xHis-Avi (3)
N-8xHis-Flag (1)
N-Avi (3)
N-His (12)
N-His-Avi (1)
N-hFc (13)
Tag Free (37)
Cat No. product name / Synonyms Species Expression System
TMPY-00523 CNTF Protein, Mouse, Recombinant (His)
CNTF Protein, Mouse, Recombinant (His)
Mouse E. coli
CNTF Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.7 kDa and the accession numbe...
TMPY-00568 CDNF Protein, Human, Recombinant (His)
CDNF Protein, Human, Recombinant (His)
Human HEK293 Cells
CDNF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is ...
TMPY-01299 GMF gamma/GMFG Protein, Human, Recombinant (His)
GMF gamma/GMFG Protein, Human, Recombinant (His)
Human E. coli
The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoieti...
TMPY-01402 NGF Protein, Mouse, Recombinant
NGF Protein, Mouse, Recombinant
Mouse CHO Cells
NGF Protein, Mouse, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P01139.
TMPY-01576 Artemin Protein, Mouse, Recombinant (hFc)
Artemin Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor ...
TMPY-01594 TNF alpha Protein, Canine, Recombinant
TNF alpha Protein, Canine, Recombinant
Canine E. coli
TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.
TMPY-01678 ARMET/MANF Protein, Human, Recombinant (His)
ARMET/MANF Protein, Human, Recombinant (His)
Human HEK293 Cells
ARMET/MANF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession numb...
TMPY-01916 CDNF Protein, Mouse, Recombinant (His)
CDNF Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
CDNF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is ...
TMPY-02069 TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
Cynomolgus,Rhesus E. coli
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number...
TMPY-02195 CNTF Protein, Rat, Recombinant
CNTF Protein, Rat, Recombinant
Rat E. coli
CNTF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.9 kDa and the accession number is P20294.
TMPY-02226 TNF alpha Protein, Ferret, Recombinant
TNF alpha Protein, Ferret, Recombinant
Ferret E. coli
TNF alpha Protein, Ferret, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A3FBF1.
TMPY-02460 LIF Protein, Mouse, Recombinant (His)
LIF Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
LIF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is...
TMPY-02732 ARMET/MANF Protein, Mouse, Recombinant (His)
ARMET/MANF Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
ARMET/MANF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession nu...
TMPY-02911 GDNF Protein, Rat, Recombinant (His)
GDNF Protein, Rat, Recombinant (His)
Rat Baculovirus Insect Cells
GDNF Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number i...
TMPY-03216 GMF beta/GMFB Protein, Human, Recombinant
GMF beta/GMFB Protein, Human, Recombinant
Human E. coli
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis...
TMPY-03555 LIF Protein, Human, Recombinant (hFc)
LIF Protein, Human, Recombinant (hFc)
Human HEK293 Cells
LIF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is...
TMPY-03917 Cardiotrophin 1 Protein, Human, Recombinant
Cardiotrophin 1 Protein, Human, Recombinant
Human HEK293 Cells
Cardiotrophin 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.2 kDa and the accession number is Q16619...
TMPY-04535 GDNF Protein, Canine, Recombinant (hFc)
GDNF Protein, Canine, Recombinant (hFc)
Canine HEK293 Cells
GDNF Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is...
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His)
TGF beta 2 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession num...
TMPY-05187 TNF alpha Protein, Mouse, Recombinant, Biotinylated
TNF alpha Protein, Mouse, Recombinant, Biotinylated
Mouse E. coli
TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession numbe...
CNTF Protein, Mouse, Recombinant (His)
TMPY-00523
CNTF Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.7 kDa and the accession numbe...
CDNF Protein, Human, Recombinant (His)
TMPY-00568
CDNF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is ...
GMF gamma/GMFG Protein, Human, Recombinant (His)
TMPY-01299
The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoieti...
NGF Protein, Mouse, Recombinant
TMPY-01402
NGF Protein, Mouse, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P01139.
Artemin Protein, Mouse, Recombinant (hFc)
TMPY-01576
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor ...
TNF alpha Protein, Canine, Recombinant
TMPY-01594
TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.
ARMET/MANF Protein, Human, Recombinant (His)
TMPY-01678
ARMET/MANF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession numb...
CDNF Protein, Mouse, Recombinant (His)
TMPY-01916
CDNF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is ...
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
TMPY-02069
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number...
CNTF Protein, Rat, Recombinant
TMPY-02195
CNTF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.9 kDa and the accession number is P20294.
TNF alpha Protein, Ferret, Recombinant
TMPY-02226
TNF alpha Protein, Ferret, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A3FBF1.
LIF Protein, Mouse, Recombinant (His)
TMPY-02460
LIF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is...
ARMET/MANF Protein, Mouse, Recombinant (His)
TMPY-02732
ARMET/MANF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession nu...
GDNF Protein, Rat, Recombinant (His)
TMPY-02911
GDNF Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number i...
GMF beta/GMFB Protein, Human, Recombinant
TMPY-03216
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis...
LIF Protein, Human, Recombinant (hFc)
TMPY-03555
LIF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is...
Cardiotrophin 1 Protein, Human, Recombinant
TMPY-03917
Cardiotrophin 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.2 kDa and the accession number is Q16619...
GDNF Protein, Canine, Recombinant (hFc)
TMPY-04535
GDNF Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is...
TGF beta 2 Protein, Rhesus, Recombinant (His)
TMPY-04577
TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession num...
TNF alpha Protein, Mouse, Recombinant, Biotinylated
TMPY-05187
TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession numbe...
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TargetMol