Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death-allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons.
Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00024 | GMF beta/GMFB Protein, Human, Recombinant (His)
GMF beta/GMFB Protein, Human, Recombinant (His)
|
Human | E. coli |
Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor... | |||
TMPJ-00081 | CNTF Protein, Human, Recombinant
CNTF Protein, Human, Recombinant
|
Human | E. coli |
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor ax... | |||
TMPJ-00086 | CT-1 Protein, Human, Recombinant (His)
CT-1 Protein, Human, Recombinant (His)
|
Human | E. coli |
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate ... | |||
TMPJ-00100 | Artemin Protein, Human, Recombinant
Artemin Protein, Human, Recombinant
|
Human | E. coli |
Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a varia... | |||
TMPJ-00124 | TNF alpha Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His)
|
Human | E. coli |
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressin... | |||
TMPJ-00125 | TNF alpha Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His)
|
Human | E. coli |
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressin... | |||
TMPJ-00134 | Pro-BDNF Protein, Human, Recombinant
pro-BDNF Protein, Human, Recombinant
|
Human | E. coli |
The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-con... | |||
TMPJ-00250 | LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-te... | |||
TMPJ-00255 | TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
|
Human | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell... | |||
TMPJ-00256 | Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell... | |||
TMPJ-00259 | TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
|
Human | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell... | |||
TMPJ-00260 | Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell... | |||
TMPJ-00622 | Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell... | |||
TMPJ-00771 | TGF beta 1 Protein, Mouse/Rat, Recombinant
TGF beta 1 Protein, Mouse/Rat, Recombinant
|
Mouse,Rat | Human Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular... | |||
TMPJ-00772 | Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
|
Mouse | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell... | |||
TMPJ-01414 | GDF-15 Protein, Mouse, Recombinant (His & Flag)
GDF-15 Protein, Mouse, Recombinant (His & Flag)
|
Mouse | Human Cells |
Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be ... | |||
TMPK-00109 | Artemin Protein, Human, Recombinant (hFc)
Artemin Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor ... | |||
TMPK-00119 | TNF alpha Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that p... | |||
TMPK-00120 | TNF alpha Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that p... | |||
TMPK-00121 | TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that p... |