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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species：
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System：
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag：
Avi (6)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Avi-His (2)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (129)
C-His-Avi (40)
C-hFc (101)
C-hFc-6xHis (2)
C-hFc-Avi (21)
C-hFc-His (1)
C-mFc (16)
C-rFc (2)
His (9)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His (1)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (3)
Cat No. product name / Synonyms Species Expression System
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc)
CD155/PVR Protein, Human, Recombinant (hFc)
 Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession num...
TMPY-04824 CTLA-4 Protein, Human, Recombinant
CTLA-4 Protein, Human, Recombinant
 Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-01386 CD155/PVR Protein, Human, Recombinant (His)
CD155/PVR Protein, Human, Recombinant (His)
 Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession num...
TMPY-01155 PD-L1 Protein, Mouse, Recombinant (His)
PD-L1 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
PD-L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number ...
TMPY-05395 PD-1 Protein, Mouse, Recombinant (hFc)
PD-1 Protein, Mouse, Recombinant (hFc)
 Mouse HEK293 Cells
PD-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number i...
TMPY-03670 PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)
PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)
 Cynomolgus,Rhesus HEK293 Cells
PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52 kDa and the accessi...
TMPY-02669 TIGIT Protein, Mouse, Recombinant (His)
TIGIT Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
TIGIT Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number ...
TMPY-00237 PD-L1 Protein, Canine, Recombinant (hFc)
PD-L1 Protein, Canine, Recombinant (hFc)
 Canine HEK293 Cells
PD-L1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.5 kDa and the accession number...
TMPY-04939 LAG-3 Protein, Human, Recombinant
LAG-3 Protein, Human, Recombinant
 Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04898 PD-1 Protein, Human, Recombinant (hFc)
PD-1 Protein, Human, Recombinant (hFc)
 Human HEK293 Cells
PD-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number i...
TMPY-01604 CTLA-4 Protein, Mouse, Recombinant (His)
CTLA-4 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
CTLA-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.46 kDa and the accession numbe...
TMPY-03219 VISTA Protein, Human, Recombinant (His)
VISTA Protein, Human, Recombinant (His)
 Human HEK293 Cells
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number ...
TMPY-06094 PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)
 Cynomolgus,Rhesus HEK293 Cells
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the acce...
TMPY-01180 CD86 Protein, Human, Recombinant (His)
CD86 Protein, Human, Recombinant (His)
 Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number i...
TMPY-05260 PD-1 Protein, Cynomolgus, Recombinant (His)
PD-1 Protein, Cynomolgus, Recombinant (His)
 Cynomolgus HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession num...
TMPY-05322 B7-H4 Protein, Mouse, Recombinant (His)
B7-H4 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number ...
TMPY-01612 CD155/PVR Protein, Rhesus, Recombinant (His)
CD155/PVR Protein, Rhesus, Recombinant (His)
 Rhesus HEK293 Cells
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession nu...
TMPY-04730 LAG-3 Protein, Human, Recombinant (His)
LAG-3 Protein, Human, Recombinant (His)
 Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number ...
TMPY-04957 PD-L2 Protein, Human, Recombinant (His), Biotinylated
PD-L2 Protein, Human, Recombinant (His), Biotinylated
 Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the acces...
TMPY-04064 B7-H3 Protein, Mouse, Recombinant (His)
B7-H3 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.9 kDa and the accession number ...
CD155/PVR Protein, Human, Recombinant (hFc)
TMPY-00699
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession num...
CTLA-4 Protein, Human, Recombinant
TMPY-04824
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
CD155/PVR Protein, Human, Recombinant (His)
TMPY-01386
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession num...
PD-L1 Protein, Mouse, Recombinant (His)
TMPY-01155
PD-L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number ...
PD-1 Protein, Mouse, Recombinant (hFc)
TMPY-05395
PD-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number i...
PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)
TMPY-03670
PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52 kDa and the accessi...
TIGIT Protein, Mouse, Recombinant (His)
TMPY-02669
TIGIT Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number ...
PD-L1 Protein, Canine, Recombinant (hFc)
TMPY-00237
PD-L1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.5 kDa and the accession number...
LAG-3 Protein, Human, Recombinant
TMPY-04939
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
PD-1 Protein, Human, Recombinant (hFc)
TMPY-04898
PD-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number i...
CTLA-4 Protein, Mouse, Recombinant (His)
TMPY-01604
CTLA-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.46 kDa and the accession numbe...
VISTA Protein, Human, Recombinant (His)
TMPY-03219
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number ...
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06094
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the acce...
CD86 Protein, Human, Recombinant (His)
TMPY-01180
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number i...
PD-1 Protein, Cynomolgus, Recombinant (His)
TMPY-05260
PD-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession num...
B7-H4 Protein, Mouse, Recombinant (His)
TMPY-05322
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number ...
CD155/PVR Protein, Rhesus, Recombinant (His)
TMPY-01612
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession nu...
LAG-3 Protein, Human, Recombinant (His)
TMPY-04730
LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number ...
PD-L2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04957
PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the acces...
B7-H3 Protein, Mouse, Recombinant (His)
TMPY-04064
B7-H3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.9 kDa and the accession number ...
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