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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species：
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System：
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag：
Avi (6)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Avi-His (2)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (129)
C-His-Avi (40)
C-hFc (101)
C-hFc-6xHis (2)
C-hFc-Avi (21)
C-hFc-His (1)
C-mFc (16)
C-rFc (2)
His (9)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His (1)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (3)
Cat No. product name / Synonyms Species Expression System
TMPY-04345 PD-L1 Protein, Rat, Recombinant (His)
PD-L1 Protein, Rat, Recombinant (His)
 Rat HEK293 Cells
PD-L1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is...
TMPY-04949 PD-L1 Protein, Human, Recombinant (His), Biotinylated
PD-L1 Protein, Human, Recombinant (His), Biotinylated
 Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the acc...
TMPY-04683 CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant
 Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-02031 B7-H3 Protein, Human, Recombinant (His)
B7-H3 Protein, Human, Recombinant (His)
 Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is...
TMPY-05372 FGL1 Protein, Human, Recombinant (His)
FGL1 Protein, Human, Recombinant (His)
 Human Baculovirus Insect Cells
FGL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number...
TMPY-00674 B7-1 Protein, Human, Recombinant
B7-1 Protein, Human, Recombinant
 Human HEK293 Cells
B7-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is A0N0P2.
TMPY-05276 CD47 Protein, Cynomolgus, Recombinant (hFc)
CD47 Protein, Cynomolgus, Recombinant (hFc)
 Cynomolgus HEK293 Cells
CD47 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession num...
TMPY-05227 TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
 Human HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kD...
TMPY-05815 PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
 Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 19.41 ...
TMPY-04262 B7-H3 Protein, Human, Recombinant (His), Biotinylated
B7-H3 Protein, Human, Recombinant (His), Biotinylated
 Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the acces...
TMPY-00996 PD-1 Protein, Mouse, Recombinant (His)
PD-1 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
PD-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number i...
TMPY-02476 CD96 Protein, Mouse, Recombinant (His)
CD96 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
CD96 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58 kDa and the accession number is ...
TMPY-05208 PD-L1 Protein, Human, Recombinant
PD-L1 Protein, Human, Recombinant
 Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)
TIGIT Protein, Human, Recombinant (hFc)
 Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number ...
TMPY-02011 CD96 Protein, Human, Recombinant (His)
CD96 Protein, Human, Recombinant (His)
 Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is ...
TMPY-00130 VISTA Protein, Mouse, Recombinant (hFc)
VISTA Protein, Mouse, Recombinant (hFc)
 Mouse HEK293 Cells
VISTA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.5 kDa and the accession number ...
TMPY-01621 TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
 Human HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the acce...
TMPY-05343 CD47 Protein, Cynomolgus, Rhesus, Recombinant (His)
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His)
 Cynomolgus,Rhesus HEK293 Cells
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the acces...
TMPY-05827 PD-L2 Protein, Human, Recombinant (mFc)
PD-L2 Protein, Human, Recombinant (mFc)
 Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number...
TMPY-04989 Galectin-9 Protein, Human, Recombinant (hFc)
Galectin-9 Protein, Human, Recombinant (hFc)
 Human HEK293 Cells
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding p...
PD-L1 Protein, Rat, Recombinant (His)
TMPY-04345
PD-L1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is...
PD-L1 Protein, Human, Recombinant (His), Biotinylated
TMPY-04949
PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the acc...
CD47 Protein, Human, Recombinant
TMPY-04683
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
B7-H3 Protein, Human, Recombinant (His)
TMPY-02031
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is...
FGL1 Protein, Human, Recombinant (His)
TMPY-05372
FGL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number...
B7-1 Protein, Human, Recombinant
TMPY-00674
B7-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is A0N0P2.
CD47 Protein, Cynomolgus, Recombinant (hFc)
TMPY-05276
CD47 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession num...
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-05227
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kD...
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
TMPY-05815
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 19.41 ...
B7-H3 Protein, Human, Recombinant (His), Biotinylated
TMPY-04262
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the acces...
PD-1 Protein, Mouse, Recombinant (His)
TMPY-00996
PD-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number i...
CD96 Protein, Mouse, Recombinant (His)
TMPY-02476
CD96 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58 kDa and the accession number is ...
PD-L1 Protein, Human, Recombinant
TMPY-05208
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number ...
CD96 Protein, Human, Recombinant (His)
TMPY-02011
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is ...
VISTA Protein, Mouse, Recombinant (hFc)
TMPY-00130
VISTA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.5 kDa and the accession number ...
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TMPY-01621
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the acce...
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-05343
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the acces...
PD-L2 Protein, Human, Recombinant (mFc)
TMPY-05827
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number...
Galectin-9 Protein, Human, Recombinant (hFc)
TMPY-04989
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding p...
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