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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species：
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System：
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag：
Avi (6)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Avi-His (2)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (129)
C-His-Avi (40)
C-hFc (101)
C-hFc-6xHis (2)
C-hFc-Avi (21)
C-hFc-His (1)
C-mFc (16)
C-rFc (2)
His (9)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His (1)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (3)
Cat No. product name / Synonyms Species Expression System
TMPY-06328 CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
 Mouse HEK293 Cells
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.1 kD...
TMPY-06336 PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
 Human HEK293 Cells
PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.49 k...
TMPY-06367 CD47 Protein, Human, Recombinant (aa 19-139, His)
CD47 Protein, Human, Recombinant (aa 19-139, His)
 Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.17kDa and the accessi...
TMPY-06397 CD96 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD96 Protein, Human, Recombinant (hFc & Avi), Biotinylated
 Human HEK293 Cells
CD96 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 82.09 k...
TMPY-06462 TIGIT Protein, Human, Recombinant (aa 22-141, His)
TIGIT Protein, Human, Recombinant (aa 22-141, His)
 Human CHO Cells
TIGIT Protein, Human, Recombinant (aa 22-141, His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 14.51 kDa and the accessio...
TMPY-06537 BTN1A1 Protein, Mouse, Recombinant (His)
BTN1A1 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
BTN1A1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.96 kDa and the accession numbe...
TMPY-06542 BTN1A1 Protein, Human, Recombinant (His)
BTN1A1 Protein, Human, Recombinant (His)
 Human HEK293 Cells
BTN1A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.39 kDa and the accession numbe...
TMPY-06543 BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated
BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated
 Human HEK293 Cells
BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.20...
TMPY-06546 BTN1A1 Protein, Human, Recombinant (hFc)
BTN1A1 Protein, Human, Recombinant (hFc)
 Human HEK293 Cells
BTN1A1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.67 kDa and the accession numbe...
TMPY-06581 B7-H3 Protein, Human, Recombinant (isoform 2, His)
B7-H3 Protein, Human, Recombinant (isoform 2, His)
 Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (isoform 2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.52 kDa and the acces...
TMPY-06682 PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)
 Human HEK293 Cells
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and...
TMPY-06711 B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
 Mouse HEK293 Cells
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.94 k...
TMPY-06772 IDO Protein, Mouse, Recombinant (His)
IDO Protein, Mouse, Recombinant (His)
 Mouse E. coli
IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession numbe...
TMPY-06819 PD-L2 Protein, Rhesus, Recombinant (hFc)
PD-L2 Protein, Rhesus, Recombinant (hFc)
 Rhesus HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number...
TMPY-06824 CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
 Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.89...
TMPY-06829 BTLA Protein, Human, Recombinant (isoform 1,mFc)
BTLA Protein, Human, Recombinant (isoform 1,mFc)
 Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform 1,mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.56 kDa and the accessi...
TMPY-06838 PD-L2 Protein, Rhesus, Recombinant (His)
PD-L2 Protein, Rhesus, Recombinant (His)
 Rhesus HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number i...
TMPY-06847 Siglec-9 Protein, Human, Recombinant (His)
Siglec-9 Protein, Human, Recombinant (His)
 Human HEK293 Cells
Siglec-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.48 kDa and the accession num...
TMPY-06880 CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
 Human HEK293 Cells
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.42 k...
TMPY-06894 VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
 Human HEK293 Cells
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 ...
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06328
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.1 kD...
PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06336
PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.49 k...
CD47 Protein, Human, Recombinant (aa 19-139, His)
TMPY-06367
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.17kDa and the accessi...
CD96 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06397
CD96 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 82.09 k...
TIGIT Protein, Human, Recombinant (aa 22-141, His)
TMPY-06462
TIGIT Protein, Human, Recombinant (aa 22-141, His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 14.51 kDa and the accessio...
BTN1A1 Protein, Mouse, Recombinant (His)
TMPY-06537
BTN1A1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.96 kDa and the accession numbe...
BTN1A1 Protein, Human, Recombinant (His)
TMPY-06542
BTN1A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.39 kDa and the accession numbe...
BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06543
BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.20...
BTN1A1 Protein, Human, Recombinant (hFc)
TMPY-06546
BTN1A1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.67 kDa and the accession numbe...
B7-H3 Protein, Human, Recombinant (isoform 2, His)
TMPY-06581
B7-H3 Protein, Human, Recombinant (isoform 2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.52 kDa and the acces...
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)
TMPY-06682
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and...
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06711
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.94 k...
IDO Protein, Mouse, Recombinant (His)
TMPY-06772
IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession numbe...
PD-L2 Protein, Rhesus, Recombinant (hFc)
TMPY-06819
PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number...
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06824
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.89...
BTLA Protein, Human, Recombinant (isoform 1,mFc)
TMPY-06829
BTLA Protein, Human, Recombinant (isoform 1,mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.56 kDa and the accessi...
PD-L2 Protein, Rhesus, Recombinant (His)
TMPY-06838
PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number i...
Siglec-9 Protein, Human, Recombinant (His)
TMPY-06847
Siglec-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.48 kDa and the accession num...
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06880
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.42 k...
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06894
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 ...
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