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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species：
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System：
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag：
Avi (6)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Avi-His (2)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (129)
C-His-Avi (40)
C-hFc (101)
C-hFc-6xHis (2)
C-hFc-Avi (21)
C-hFc-His (1)
C-mFc (16)
C-rFc (2)
His (9)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His (1)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (3)
Cat No. product name / Synonyms Species Expression System
TMPY-06907 CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
 Human HEK293 Cells
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 61.04 k...
TMPY-06909 B7-1 Protein, Rat, Recombinant (His)
B7-1 Protein, Rat, Recombinant (His)
 Rat HEK293 Cells
B7-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.38 kDa and the accession number is...
TMPY-06913 BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
 Human HEK293 Cells
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17 kDa....
TMPY-06922 BTLA Protein, Human, Recombinant (isoform1, His)
BTLA Protein, Human, Recombinant (isoform1, His)
 Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.19 kDa and the accessi...
TMPY-06923 BTLA Protein, Mouse, Recombinant (His)
BTLA Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
BTLA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.54 kDa and the accession number ...
TMPY-06930 BTLA Protein, Human, Recombinant (isoform1,hFc)
BTLA Protein, Human, Recombinant (isoform1,hFc)
 Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.47 kDa and the accessio...
TMPY-06931 LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
 Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 ...
TMPY-06966 Siglec-9 Protein, Human, Recombinant (His & hFc)
Siglec-9 Protein, Human, Recombinant (His & hFc)
 Human HEK293 Cells
Siglec-9 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 64.13 kDa and the...
TMPY-06977 PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
 Mouse HEK293 Cells
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.02 ...
TMPY-06978 TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
 Mouse HEK293 Cells
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 16.01 ...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)
CTLA-4 Protein, Human, Recombinant (His)
 Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number i...
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
 Cynomolgus,Rhesus HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the acce...
TMPY-04343 PD-L1 Protein, Human, Recombinant (His)
PD-L1 Protein, Human, Recombinant (His)
 Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number ...
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His)
CD47 Protein, Human, Recombinant (aa 1-139, His)
 Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accessio...
TMPY-04810 CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His)
 Mouse HEK293 Cells
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number i...
TMPY-01302 CD200R Protein, Human, Recombinant (His)
CD200R Protein, Human, Recombinant (His)
 Human HEK293 Cells
CD200R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number...
TMPY-03093 CD47 Protein, Rat, Recombinant (His)
CD47 Protein, Rat, Recombinant (His)
 Rat HEK293 Cells
CD47 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is ...
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)
PD-L2 Protein, Human, Recombinant (His)
 Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is...
TMPY-00897 PD-1 Protein, Human, Recombinant (His)
PD-1 Protein, Human, Recombinant (His)
 Human HEK293 Cells
PD-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number i...
TMPY-03524 B7-H4 Protein, Human, Recombinant (His)
B7-H4 Protein, Human, Recombinant (His)
 Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number ...
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06907
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 61.04 k...
B7-1 Protein, Rat, Recombinant (His)
TMPY-06909
B7-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.38 kDa and the accession number is...
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06913
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17 kDa....
BTLA Protein, Human, Recombinant (isoform1, His)
TMPY-06922
BTLA Protein, Human, Recombinant (isoform1, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.19 kDa and the accessi...
BTLA Protein, Mouse, Recombinant (His)
TMPY-06923
BTLA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.54 kDa and the accession number ...
BTLA Protein, Human, Recombinant (isoform1,hFc)
TMPY-06930
BTLA Protein, Human, Recombinant (isoform1,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.47 kDa and the accessio...
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06931
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 ...
Siglec-9 Protein, Human, Recombinant (His & hFc)
TMPY-06966
Siglec-9 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 64.13 kDa and the...
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06977
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.02 ...
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06978
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 16.01 ...
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number i...
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06074
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the acce...
PD-L1 Protein, Human, Recombinant (His)
TMPY-04343
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number ...
CD47 Protein, Human, Recombinant (aa 1-139, His)
TMPY-04935
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accessio...
CD47 Protein, Mouse, Recombinant (His)
TMPY-04810
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number i...
CD200R Protein, Human, Recombinant (His)
TMPY-01302
CD200R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number...
CD47 Protein, Rat, Recombinant (His)
TMPY-03093
CD47 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is ...
PD-L2 Protein, Human, Recombinant (His)
TMPY-04346
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is...
PD-1 Protein, Human, Recombinant (His)
TMPY-00897
PD-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number i...
B7-H4 Protein, Human, Recombinant (His)
TMPY-03524
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number ...
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