Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR0987 is a RORγt agonist,
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 228.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 589.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | SR0987 is a RORγt agonist, |
Targets&IC50 | RORγt:800 nM (EC50) |
In vitro | Treatment with SR0987 leads to a significant decrease in the surface expression of PD-1, while desmosterol shows no impact on this parameter. Co-treatment with SR0987 and desmosterol suggests a potential increase in IL17 production. Additionally, SR0987 exhibits a concentration-dependent stimulation of reporter gene expression, achieving an effective concentration (EC50) of approximately 800nM. |
Molecular Weight | 397.7 |
Formula | C16H10ClF6NO2 |
CAS No. | 303126-97-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (113.15 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SR0987 303126-97-8 Metabolism ROR SR 0987 Inhibitor SR-0987 inhibit RAR-related orphan receptor inhibitor