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TargetMol | Compound Library

Nuclear Receptor Compound Library

Catalog No. L1510

Nuclear receptors are a class of proteins, different from membrane receptors located in the cell membrane, found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors, thereby controlling the development, homeostasis, and metabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization and underlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease. TargetMol collects 531 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1510

Nuclear Receptor Compound Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

PPAR
Estrogen/progestogen Receptor
Estrogen Receptor/ERR
Autophagy
Androgen Receptor
Glucocorticoid Receptor
Endogenous Metabolite
Retinoid Receptor
Apoptosis
ROR
Thyroid hormone receptor(THR)
Progesterone Receptor
FXR
AhR
Antibacterial
Liver X Receptor
COX
Aryl Hydrocarbon Receptor
P450
NF-κB
Ferroptosis
Reactive Oxygen Species
Antifungal
GPR
RAR/RXR 
Drug Metabolite
Akt
AMPK
Potassium Channel
Mitophagy
Parasite
Adrenergic Receptor
Annexin A
MMP
Prostaglandin Receptor
TSH Receptor
Influenza Virus
Antibiotic
Reductase
JNK
TRP/TRPV Channel
IL Receptor
Lipoxygenase
GPCR19
Tyrosinase
HIV Protease
p38 MAPK
Glutathione Peroxidase
Phosphatase
Virus Protease
PARP
VEGFR
PKC
PDE
ROS
Smo
BCL
Interleukin
SARS-CoV
Sirtuin
transporter
Nrf2
Aromatase
GABA Receptor
TNF
Cannabinoid Receptor
AChR
p53
NO Synthase
Proteasome
Adenylyl cyclase
NOS
Carbonic Anhydrase
Histone Methyltransferase
HCV Protease
Ligands for Target Protein for PROTAC
Dehydrogenase
c-Met/HGFR
Antioxidant
GSK-3
Melatonin Receptor
ABC
MRP
PKA
HBV
Wnt/beta-catenin
Cysteine Protease
Leukotriene Receptor
Glucokinase
Caspase
Calcium Channel
ERK
MAO
FLAP
LDL
Gamma-secretase
Phosphorylase
Glucosidase
Antifection
Opioid Receptor
PAK
Epoxide Hydrolase
GluR
Epigenetic Reader Domain
CaMK
EGFR
DNA/RNA Synthesis
STAT
Ligand for E3 Ligase
Phospholipase
Complement System
FLT
c-Kit
Sodium Channel
DNA Methyltransferase
TAM Receptor
Thrombin
HIF/HIF Prolyl-Hydroxylase
HER
S1P Receptor

Keywords