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TargetMol | Compound Library

Apoptosis Compound Library

Catalog No. L9000

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's lifecycle. Apoptosis leads to characteristic cell changes (morphology): the cell breaks apart into multiple vesicles called apoptotic bodies, which undergo phagocytosis. Apoptosis is regulated by both pro-apoptotic (such as Fas receptor and caspases) and anti-apoptotic (such as Bcl-2 and IAP) factors. Disordered apoptosis is implicated in a variety of human diseases. Inhibition of apoptosis can result in a number of cancers, autoimmune diseases, inflammatory diseases, and viral infections. Excessive apoptosis may also be a feature of some conditions such as autoimmune diseases, neurodegenerative diseases, and ischemia-associated injury. Consequently, considerable interest has arisen in therapeutic strategies for cancer, autoimmune diseases, and neurodegenerative diseases by modulating apoptosis pharmacologically. TargetMol's collection of 2394 apoptosis-related compounds, Apoptosis Compound Library, is divided accordingly with compounds designed for either pro- or anti-apoptosis purposes and can be used for research in cancer and neurodegenerative diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9000

Apoptosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2394 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
  • Targets include Bcl-2, Caspase, p53, TNF-alpha, and surviving, etc.;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
Endogenous Metabolite
EGFR
TNF
Antibacterial
NF-κB
Caspase
Ferroptosis
Bcl-2 Family
Reactive Oxygen Species
JAK
STAT
CDK
MDM-2/p53
Akt
p38 MAPK
COX
PI3K
ERK
DNA/RNA Synthesis
Ras
VEGFR
Parasite
p53
Antibiotic
Raf
Antioxidant
IL Receptor
Microtubule Associated
Antifungal
HDAC
FLT
Src
RIP kinase
JNK
mTOR
Interleukin
c-RET
MEK
HIV Protease
Mitophagy
AMPK
PERK
PARP
PDGFR
MAPK
FGFR
E1/E2/E3 Enzyme
c-Kit
Dehydrogenase
Nucleoside Antimetabolite/Analog
Tyrosine Kinases
Aurora Kinase
Epigenetic Reader Domain
HSP
Influenza Virus
Mdm2
Nrf2
Virus Protease
Topoisomerase
Bcr-Abl
c-Met/HGFR
PPAR
PKC
Mitochondrial Metabolism
Cytochromes P450
Phosphatase
GSK-3
Wnt/beta-catenin
Potassium Channel
PD-1/PD-L1
NO Synthase
Pim
Proteasome
ROS
IAP
MMP
Sirtuin
HER
Histone Methyltransferase
Calcium Channel
IκB/IKK
Lipoxygenase
IGF-1R
HSV
FAK
PDE
Anti-infection
Estrogen Receptor/ERR
Molecular Glues
TGF-beta/Smad
SARS-CoV
AChR
HIF/HIF Prolyl-Hydroxylase
ATPase
DNA-PK
Estrogen/progestogen Receptor
DNA Alkylator/Crosslinker
RAAS
Chk
DUB
P-gp
Beta Amyloid
Kras
Syk
S6 Kinase
PROTACs
Necroptosis
PKA
Cholinesterase (ChE)
Histone Acetyltransferase
Histone Demethylase
Bcl-6
TRP/TRPV Channel
Adrenergic Receptor
Gamma-secretase
Drug Metabolite
Antiviral
Prostaglandin Receptor
TLR
ALK
Casein Kinase
PDK
Phospholipase
5-HT Receptor
HMG-CoA Reductase
Dopamine Receptor
Histamine Receptor
OXPHOS
Trk receptor
Pyroptosis
Retinoid Receptor
Ligand for E3 Ligase
c-Fms
HIF
Sodium Channel
Tyrosinase
GPCR
NADPH
Rho
Serine Protease
ASK
ATM/ATR
Reverse Transcriptase
GABA Receptor
DNA Methyltransferase
TAM Receptor
NOD-like Receptor (NLR)
S1P Receptor
Monoamine Oxidase
NOS
HCV Protease
Integrin
Glutathione Peroxidase
HBV
UGT
DNA Alkylation
PTEN
CaMK
Telomerase
Survivin
PLK
Kinesin
Transferase
LPL Receptor
Tie-2
c-Myc
Cysteine Protease
MAO
Immunology/Inflammation related
iGluR
Fatty Acid Synthase
GluR
DAPK
Reductase
MRP
Antifolate
Antifection
Opioid Receptor
Angiotensin-converting Enzyme (ACE)
ROS Kinase
MLK
ADC Cytotoxin
Proton pump
Ligands for Target Protein for PROTAC
IFNAR
DYRK
TOPK
Photosensitizer
Cell Cycle Arrest
FXR
ROCK
CSF-1R
IRE1
Glucosidase
DPP-4
IKZF
PAK
DNA
Androgen Receptor
PGE Synthase
MNK
transporter
PAI-1
GST
GPX
Cuproptosis
SGK
MicroRNA
DHFR
ROR
CRM1
Amino Acids and Derivatives
YAP
LTR
Adenosine Receptor
BACE
Cholecystokinin Receptor
Serine/threonin kinase
Liver X Receptor
Leukotriene Receptor
PYK2
NR4A
Aryl Hydrocarbon Receptor
IDO
LDL
P2X Receptor
BTK
Hexokinase
Hedgehog/Smoothened
CXCR
Xanthine Oxidase
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
Wee1
Lipid
Beta-Secretase
Free radical scavengers
p62
FKBP
CRISPR/Cas9
FOXO
NADPH-oxidase
NOD
Sigma receptor
FOXO3
Carbonic Anhydrase
OCT
Hck
ATG
NAMPT
Glucokinase
Glucocorticoid Receptor
Prolyl Endopeptidase (PREP)
FLAP
PAFR
Fas/FasL
NMDAR
ABC Transporter
Smo
Stearoyl-CoA Desaturase (SCD)
Endothelin Receptor
PAD
KSP
cAMP
Acyltransferase
STING
LRRK2
Aminopeptidase
AIM2
Hippo pathway
Aromatase
KLF
PI4K
BMI-1
IRAK
p97
CFTR
Apelin receptor
Chloride channel
Hydrogenase
RAR/RXR
MALT
GDNF
NEDD8
Dynamin
Y Box Binding Protein 1
P2Y Receptor
Na+/Ca2+ Exchanger
Lipase
gp120/CD4
MIF
GTPase
VDA
Progesterone Receptor
Melatonin Receptor
GNRH Receptor
ASCT
VDAC
Serotonin Transporter
Glutaminase
LDLR
RANKL/RANK
Amylase
SIK
Myosin
MTH1
DNA gyrase
Na-K-Cl cotransporter
Monoamine Transporter
Guanylate cyclase
PROTAC Linker
Thioredoxin
FAAH
CCR
ACK1
Somatostatin
OX Receptor
Cadherin
Transketolase
Norepinephrine
Target Protein Ligand-Linker Conjugate
Glutathione reductase
GPCR19
Urea Transporter
Ephrin Receptor
hCE
HuR
MELK
RSV
Neprilysin
Protease
LPA Receptor
Melanocortin Receptor
Hydroxylase
Adenosine Deaminase
Cannabinoid Receptor
Platelet aggregation
APC/C
Thrombin
Protease-activated Receptor
Lysosomal Autophagy
Liposome
Imidazoline Receptor
PKM
Ferroportin
Vitamin
PGC-1α

Keywords