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Rapastinel

Catalog No. T3407 CAS 117928-94-6

Synonyms: TPPT-amide, GLYX-13, 雷帕替奈, Thr-Pro-Pro-Thr-NH2

Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.

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Rapastinel, CAS 117928-94-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.

Synonyms	TPPT-amide, GLYX-13, 雷帕替奈, Thr-Pro-Pro-Thr-NH2
Molecular Weight	413.475
Formula	C18H31N5O6
CAS No.	117928-94-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 32 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Burgdorf J, et al. Neuroscience. 2015 Nov 12;308:202-11.

Related Products

Related compounds with same targets

Orphenadrine Citrate BDZ-g AMPA receptor antagonist-3 AMPA receptor antagonist-2 Rapastinel UBP310 CP 465022 hydrochloride SYM 2081

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Rapastinel 117928-94-6 离子通道神经科学 iGluR NMDAR Thr-Pro-Pro-Thr-NH2 Inhibitor inhibit GLYX-13 GLYX 13 GLYX13 TPPT-amide Ionotropic glutamate receptors inhibitor

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