Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Monacolin J

Monacolin J
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.
Catalog No. T12092Cas No. 79952-42-4
Select Batch
Purity:98.87%
Contact us for more batch information
Resource Download

Monacolin J

Catalog No. T12092Cas No. 79952-42-4
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$72In Stock
5 mg$163In Stock
10 mg$247In Stock
25 mg$418In Stock
50 mg$596In Stock
100 mg$863In Stock
1 mL x 10 mM (in DMSO)$173In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Monacolin J"

Product Introduction

Bioactivity
Description
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.
In vitro
Monacolin J is a cholesterol biosynthesis inhibitor, and inhibits the activity of HMG-CoA reductase. Na salt of Monacolin J causes 50% inhibition on reductase at 1.2 μg/mL[1].
AliasAntibiotic MB 530A, Lovastatin diol lactone
Chemical Properties
Molecular Weight320.42
FormulaC19H28O4
Cas No.79952-42-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (171.65 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1209 mL15.6045 mL31.2090 mL156.0452 mL
5 mM0.6242 mL3.1209 mL6.2418 mL31.2090 mL
10 mM0.3121 mL1.5605 mL3.1209 mL15.6045 mL
20 mM0.1560 mL0.7802 mL1.5605 mL7.8023 mL
50 mM0.0624 mL0.3121 mL0.6242 mL3.1209 mL
100 mM0.0312 mL0.1560 mL0.3121 mL1.5605 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Monacolin J | purchase Monacolin J | Monacolin J cost | order Monacolin J | Monacolin J chemical structure | Monacolin J in vitro | Monacolin J formula | Monacolin J molecular weight