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TargetMol | Compound Library

Neuroprotective Compound Library

Catalog No. L2640

Neuroprotection refers to the process of safeguarding the nervous system's functionality by preventing neuronal damage or promoting neuronal repair through various mechanisms and approaches. Research in this field primarily focuses on preventing neuronal apoptosis, reducing inflammatory responses, mitigating oxidative stress, and fostering neural regeneration. Neuroprotection holds significant implications for numerous neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, multiple sclerosis) and acute neurological injuries (like stroke and spinal cord injury). Studies have unveiled several critical targets, including antioxidants, neurotrophic factors, calcium ion channels, and others, which show potential in preventing neuronal injury, promoting neural regeneration, and combating neurodegenerative diseases.

TargetMol Neuroprotective Compound Library has compiled 1120 compounds with demonstrated neuroprotective activity and potential neuroprotective capabilities. This library can be utilized for drug development related to neuroprotection and for exploring mechanisms associated with neuroprotective actions.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2640

Neuroprotective Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1120 bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);
  • Targets include Brain-Derived Neurotrophic Factor (BDNF), Calcium Channels, Sodium Channels, N-methyl-D-aspartate receptors (NMDAR), Transient Receptor Potential Melastatin 4 (TRPM4), among others;
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Calcium Channel
Apoptosis
Sodium Channel
Wnt/beta-catenin
Potassium Channel
NO Synthase
iGluR
Autophagy
Endogenous Metabolite
GSK-3
GABA Receptor
ROS
NF-κB
NMDAR
GluR
AMPK
Antibacterial
Reactive Oxygen Species
COX
AChR
Akt
Parasite
ERK
Caspase
CDK
Cytochromes P450
5-HT Receptor
TNF
NOS
PARP
Beta Amyloid
Antioxidant
Cholinesterase (ChE)
Interleukin
Dopamine Receptor
p38 MAPK
PDE
PI3K
IL Receptor
TRP/TRPV Channel
Adrenergic Receptor
Monoamine Oxidase
PPAR
mTOR
Histamine Receptor
Bcl-2 Family
HIF/HIF Prolyl-Hydroxylase
Prostaglandin Receptor
DNA/RNA Synthesis
Influenza Virus
Mitophagy
Antibiotic
PKC
STAT
JNK
Ferroptosis
Adenosine Receptor
MAO
Tyrosinase
TGF-beta/Smad
EGFR
Mitochondrial Metabolism
MMP
P-gp
Nrf2
MEK
Anti-infection
Virus Protease
PKA
Glucosidase
Antifungal
MAPK
Ras
Phosphatase
S6 Kinase
Microtubule Associated
ATPase
HSV
Sigma receptor
HIV Protease
RAAS
Na+/Ca2+ Exchanger
TLR
Lipid
Carbonic Anhydrase
Src
glycosidase
Casein Kinase
HDAC
SARS-CoV
GPCR
Serine Protease
VEGFR
Gamma-secretase
Serine/threonin kinase
Molecular Glues
CaMK
transporter
Drug Metabolite
Antifection
Aurora Kinase
PERK
E1/E2/E3 Enzyme
Porcupine
Serotonin Transporter
JAK
Epigenetic Reader Domain
Phospholipase
Lipoxygenase
NOD
Immunology/Inflammation related
Chk
Trk receptor
S1P Receptor
Chloride channel
Cysteine Protease
Opioid Receptor
PTEN
Norepinephrine
Pyroptosis
Cannabinoid Receptor
Glucocorticoid Receptor
Antiviral
FLT
Estrogen/progestogen Receptor
PGE Synthase
IGF-1R
Sirtuin
Imidazoline Receptor
Estrogen Receptor/ERR
Beta-Secretase
DYRK
MDM-2/p53
RSV
HCV Protease
Leukotriene Receptor
Amylase
Aryl Hydrocarbon Receptor
Topoisomerase
LDL
Guanylate cyclase
Xanthine Oxidase
LRRK2
p53
Dehydrogenase
BACE
ROCK
Stearoyl-CoA Desaturase (SCD)
PDK
AhR
LPL Receptor
Bcr-Abl
P2X Receptor
Somatostatin
Survivin
FGFR
HMG-CoA Reductase
NR4A
Monoamine Transporter
ATP Citrate Lyase
Proteasome
Integrin
Reductase
HSP
IκB/IKK
Arginase
cAMP
HIF
ROS Kinase
PD-1/PD-L1
FOXO3
PGK1
Amino Acids and Derivatives
Cell Cycle Arrest
Glucokinase
DPP-4
Angiotensin-converting Enzyme (ACE)
DUB
GPCR19
c-Fms
Proton pump
Arrestin
Prolyl Endopeptidase (PREP)
DNA gyrase
CXCR
OXPHOS
STING
Acetyl-CoA Carboxylase
FKBP
Retinoid Receptor
NADPH-oxidase
Glyoxalase
Piezo Channel
YAP
Necroptosis
OCT
RANKL/RANK
IDO
Raf
Telomerase
SGLT
DNA Methyltransferase
NOD-like Receptor (NLR)
Adenylyl Cyclase
MRP
Glutaminase
RIP kinase
UGT
Fatty Acid Synthase
OX Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
Methionine Adenosyltransferase (MAT)
DAPK
LTR
Histone Demethylase
HBV
Tyrosine Kinases
Nucleoside Antimetabolite/Analog
PDGFR
Hippo pathway
Kras
ribosome
Thyroid hormone receptor(THR)
DHFR
Cholecystokinin Receptor
CSF-1R
Myosin
Adenosine Deaminase
TAM Receptor
c-Met/HGFR
gp120/CD4
GTPase
Progesterone Receptor
c-Myc
CaSR
ASCT
Liver X Receptor
NAMPT
HCN Channel
Ephrin Receptor
Histone Acetyltransferase
GST
Sodium-dependent phosphate transporter

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