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TargetMol | Compound Library

Neuroprotective Compound Library

Catalog No. L2640

Neuroprotection refers to the process of safeguarding the nervous system's functionality by preventing neuronal damage or promoting neuronal repair through various mechanisms and approaches. Research in this field primarily focuses on preventing neuronal apoptosis, reducing inflammatory responses, mitigating oxidative stress, and fostering neural regeneration. Neuroprotection holds significant implications for numerous neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, multiple sclerosis) and acute neurological injuries (like stroke and spinal cord injury). Studies have unveiled several critical targets, including antioxidants, neurotrophic factors, calcium ion channels, and others, which show potential in preventing neuronal injury, promoting neural regeneration, and combating neurodegenerative diseases.

TargetMol Neuroprotective Compound Library has compiled 1120 compounds with demonstrated neuroprotective activity and potential neuroprotective capabilities. This library can be utilized for drug development related to neuroprotection and for exploring mechanisms associated with neuroprotective actions.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2640

Neuroprotective Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1120 bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);
  • Targets include Brain-Derived Neurotrophic Factor (BDNF), Calcium Channels, Sodium Channels, N-methyl-D-aspartate receptors (NMDAR), Transient Receptor Potential Melastatin 4 (TRPM4), among others;
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Calcium Channel
Apoptosis
Sodium Channel
Wnt/beta-catenin
Potassium Channel
NO Synthase
iGluR
Endogenous Metabolite
Autophagy
GSK-3
GABA Receptor
ROS
NF-κB
NMDAR
GluR
AMPK
Antibacterial
Reactive Oxygen Species
COX
AChR
Akt
Parasite
ERK
Caspase
CDK
5-HT Receptor
Cytochromes P450
TNF
NOS
PARP
Antioxidant
Cholinesterase (ChE)
Interleukin
Beta Amyloid
Dopamine Receptor
p38 MAPK
PI3K
PDE
IL Receptor
TRP/TRPV Channel
Monoamine Oxidase
Histamine Receptor
Mitophagy
PPAR
Adrenergic Receptor
mTOR
DNA/RNA Synthesis
Prostaglandin Receptor
Bcl-2 Family
Influenza Virus
Antibiotic
HIF/HIF Prolyl-Hydroxylase
Ferroptosis
Adenosine Receptor
JNK
PKC
MAO
STAT
TGF-beta/Smad
EGFR
Tyrosinase
Virus Protease
PKA
Mitochondrial Metabolism
Glucosidase
MMP
P-gp
Nrf2
MEK
Anti-infection
ATPase
HIV Protease
Antifungal
Na+/Ca2+ Exchanger
RAAS
Phosphatase
HSV
MAPK
Ras
S6 Kinase
Sigma receptor
Microtubule Associated
GPCR
Carbonic Anhydrase
Src
glycosidase
Lipid
SARS-CoV
TLR
transporter
Casein Kinase
HDAC
PERK
Serine Protease
Serine/threonin kinase
VEGFR
E1/E2/E3 Enzyme
Gamma-secretase
Drug Metabolite
Antifection
Molecular Glues
JAK
Aurora Kinase
Epigenetic Reader Domain
Lipoxygenase
CaMK
Porcupine
Phospholipase
NOD
Chloride channel
Estrogen/progestogen Receptor
DYRK
Estrogen Receptor/ERR
Serotonin Transporter
Cysteine Protease
Glucocorticoid Receptor
Immunology/Inflammation related
LDL
Opioid Receptor
PTEN
Chk
IGF-1R
Norepinephrine
Beta-Secretase
PGE Synthase
Antiviral
Trk receptor
Sirtuin
Pyroptosis
Cannabinoid Receptor
MDM-2/p53
FLT
HMG-CoA Reductase
Imidazoline Receptor
S1P Receptor
Proteasome
HCV Protease
Integrin
Dehydrogenase
Arginase
LPL Receptor
Reductase
BACE
Leukotriene Receptor
ROCK
NR4A
Amylase
Aryl Hydrocarbon Receptor
Topoisomerase
Bcr-Abl
P2X Receptor
Monoamine Transporter
Guanylate cyclase
Stearoyl-CoA Desaturase (SCD)
Somatostatin
Xanthine Oxidase
cAMP
ATP Citrate Lyase
Survivin
HSP
LRRK2
RSV
IκB/IKK
PDK
HIF
FGFR
ROS Kinase
AhR
p53
PD-1/PD-L1
FOXO3
PGK1
Thyroid hormone receptor(THR)
Proton pump
Adenylyl Cyclase
DHFR
Piezo Channel
Amino Acids and Derivatives
YAP
c-Met/HGFR
LTR
Arrestin
Histone Demethylase
Necroptosis
gp120/CD4
GTPase
Progesterone Receptor
OCT
c-Myc
CaSR
MRP
HBV
Cholecystokinin Receptor
Tyrosine Kinases
ASCT
Cell Cycle Arrest
Nucleoside Antimetabolite/Analog
Liver X Receptor
Glucokinase
NAMPT
Glutaminase
RANKL/RANK
IDO
CSF-1R
Prolyl Endopeptidase (PREP)
Myosin
RIP kinase
UGT
Raf
DNA gyrase
HCN Channel
DPP-4
Fatty Acid Synthase
PDGFR
CXCR
Angiotensin-converting Enzyme (ACE)
OX Receptor
DUB
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
Telomerase
SGLT
OXPHOS
STING
GPCR19
Ephrin Receptor
Histone Acetyltransferase
Methionine Adenosyltransferase (MAT)
Hippo pathway
GST
Acetyl-CoA Carboxylase
FKBP
Retinoid Receptor
Kras
c-Fms
ribosome
Adenosine Deaminase
DAPK
NADPH-oxidase
DNA Methyltransferase
TAM Receptor
NOD-like Receptor (NLR)
Glyoxalase
Sodium-dependent phosphate transporter

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