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Methyl protodioscin

Catalog No. T3771 CAS 54522-52-0

Synonyms: Smilax saponin B, NSC-698790

Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, caspase-3, and mitochondrial cytochrome c.

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Methyl protodioscin, CAS 54522-52-0

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 110.00
1 mL * 10 mM (in DMSO)	In stock	$ 130.00

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Purity: 99.57%

Purity: 99.24%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, caspase-3, and mitochondrial cytochrome c.
Source	Natural Products > Dioscoreaceae > Dioscorea

Synonyms	Smilax saponin B, NSC-698790
Molecular Weight	1063.23
Formula	C52H86O22
CAS No.	54522-52-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 94.1 mM

References and Literature

1. Ma W,et al.Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels.Atherosclerosis. 2015 Apr;239(2):566-70. 2. Bai Y,et al.Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells.Pharmacogn Mag. 2014 Jul;10(39):318-24.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Miao medicine Compound Library Natural Product Library for HTS Anti-Cancer Compound Library Anti-Tumor Natural Product Library Bioactive Compounds Library Max Traditional Mongolian Medicine Compound Library Traditional Chinese Medicine Monomer Library Natural Product Library Saccharide and Glycoside Natural Product Library

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Keywords

Methyl protodioscin 54522-52-0 Apoptosis NSC 698790 NSC698790 Smilax saponin B NSC-698790 Inhibitor inhibit inhibitor

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