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Indole-3-carbinol

Catalog No. T2947   CAS 700-06-1
Synonyms: 吲哚-3-甲醇, 3-Indolemethanol, Indole-3-Methanol, I3C, 3-吲哚甲醇

Indole-3-carbinol, a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.

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Indole-3-carbinol, CAS 700-06-1
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Indole-3-carbinol, a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
Synonyms 吲哚-3-甲醇, 3-Indolemethanol, Indole-3-Methanol, I3C, 3-吲哚甲醇
Molecular Weight 147.177
Formula C9H9NO
CAS No. 700-06-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 28 mg/mL (190.3 mM)

Ethanol: 28 mg/mL (190.3 mM)

H2O: 7 mg/mL (47.56 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Lin H, et al. Biochem Biophys Res Commun. 2015 May 1;460(2):422-7.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Compound Library Preclinical Compound Library Autophagy Compound Library HIF-1 Signaling Pathway Compound Library Glycometabolism Compound Library Anti-Cancer Metabolism Compound Library Anti-Obesity Compound Library Glutamine Metabolism Compound Library Anti-Pancreatic Cancer Compound Library Inhibitor Library

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Keywords

Indole-3-carbinol 700-06-1 NF-Kb信号通路 代谢 凋亡 泛素化 免疫与炎症 Aryl Hydrocarbon Receptor E1/E2/E3 Enzyme Endogenous Metabolite NF-κB p53 Indole-3-Methanol I3C 3-Indolemethanol Nuclear factor-κB Nuclear factor-kappaB AhR E2 conjugating enzyme Ubiquitin conjugating enzyme E3 ligating enzyme E1 activating enzyme inhibit Indole3carbinol Ubiquitin activating enzyme Inhibitor Ubiquitin ligase Indole 3 carbinol inhibitor