UBE2H Protein, Human, Recombinant (GST)

Name: UBE2H Protein, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPJ-01047
Rating: 4.5 (1 reviews)

(Synonyms: Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2) Copy Product Info

Synonyms: Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2

Catalog No. TMPJ-01047 Copy Product Info

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

Pack Size	Price	USA Stock	Global Stock
10 µg	$35	35 days	35 days
20 µg	$51	35 days	35 days
50 µg	$91	35 days	35 days
100 µg	$168	35 days	35 days
200 µg	$325	35 days	35 days
500 µg	$781	35 days	35 days
1 mg	$1,120	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 90% as determined by reducing SDS-PAGE.

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
Species	Human
Expression System	E. coli
Tag	N-GST
Accession Number	P62256
Amino Acid	Met1-Leu183
Construction	Met1-Leu183
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5.
Synonyms	Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2
Research Background	Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

Chemical Properties

Molecular Weight

50 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.