Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity.
Description | Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity. |
Molecular Weight | 328.36 |
Formula | C19H20O5 |
CAS No. | 41137-87-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Hirsutenone 41137-87-5 JAK/STAT信号通路 MAPK信号通路 NF-Kb信号通路 PI3K/Akt/mTOR信号通路 蛋白酪氨酸激酶 凋亡 免疫与炎症 微生物学 细胞骨架 血管生成 自噬 p53 PI3K IL Receptor mTOR NF-κB ERK EGFR Akt Antifection Autophagy Inhibitor inhibitor inhibit