Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has <200 fold selectivity for mTOR (IC50 = 750 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 128.00 | |
5 mg | In stock | $ 347.00 | |
10 mg | In stock | $ 563.00 | |
25 mg | In stock | $ 891.00 | |
50 mg | In stock | $ 1,230.00 | |
100 mg | In stock | $ 1,670.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 359.00 |
Description | GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM). |
Molecular Weight | 386.47 |
Formula | C18H22N6O2S |
CAS No. | 1033739-92-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (129.38 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GNE-490 1033739-92-2 Others PI3K/Akt/mTOR signaling PI3K PI3Kβ PI3Kδ Mammalian target of Rapamycin mTOR MCF7.1 PI3Kα Phosphoinositide 3-kinase GNE 490 PI3Kγ breast cancer Inhibitor GNE490 inhibit inhibitor