pi3kδ — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T35530	IHMT-PI3Kδ-372	IHMT-PI3Kδ-372	PI3K
	IHMT-PI3Kδ-372 is a selective inhibitor of PI3Kδ with an IC50 of 14 nM and can be used in studies about chronic obstructive pulmonary disease.		PI3K
T12462	PI3Kδ-IN-1		PI3K
	PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).		PI3K
T6330	Linperlisib	PI3Kδ-IN-2	PI3K
	Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3Kδ		PI3K
T5831	Selective PI3Kδ Inhibitor 1		PI3K
	Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).		PI3K
T26252	PI3Kδ-IN-3	TC KHNS 11	PI3K
	PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.		PI3K
T60196	IHMT-PI3Kδ-372 S-isomer		PI3K
	IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can ...		PI3K
T39542	PI3Kδ-IN-8	PI3Kδ-IN-8
	PI3Kδ-IN-8 is a powerful and specific oral inhibitor of PI3Kδ, exhibiting an IC50 of 3.3 nM. It demonstrates preferential inhibition of PI3Kδ when compared to PI3Kα, PI3Kβ, and PI3Kγ, with IC50 values of 377.2 nM, 241.6 ...
T39592	PI3Kδ-IN-9	PI3Kδ-IN-9
	PI3Kδ-IN-9 is a selective PI3Kδ inhibitor with an IC 50 value of 3.8 nM.
T77667	PI3Kδ-IN-16		Apoptosis , PI3K
	PI3Kδ-IN-16 is a selective and potent PI3Kδ inhibitor with anticancer and antiproliferative activity, induces cell cycle arrest and apoptosis.		Apoptosis , PI3K
T12463	PI3kδ inhibitor 1		PI3K
	PI3kδ inhibitor 1 is a selective inhibitor of PI3Kδ (IC50 of 3.8 nM).		PI3K
T81467	PI3Kδ-IN-18		PI3K
	Se15, a selective PI3Kδ inhibitor, exhibits potency with an IC50 value of less than 0.1nM and is utilized in autoimmune research [1].		PI3K
T78691	PI3Kδ-IN-12		PI3K
	PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities with pKi values of 8.0 for PI3Kδ, 6.5 for PI3Kγ, 6.4 for PI3Kβ, and 6.7 for PI3Kα. This compound is utilized in r...		PI3K
T62013	PI3Kδ-IN-10
	PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM). In hepatocellular carcinoma models, PI3Kδ-IN-10 robustly suppresses the downstream AKT pathway to induce subsequent apoptosis.
T79658	PI3Kδ-IN-14		PI3K
	PI3Kδ-IN-14 (Compound (S)-29), a selective PI3Kδ inhibitor with an IC50 of 0.8 nM and a Kd of 84.8 nM, targets the ATP-binding site within the kinase domain of PI3Kδ. This compound exhibits anti-inflammatory properties b...		PI3K
T81468	PI3Kδ-IN-17		PI3K
	PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 nM and demonstrates significant efficacy in suppressing the proliferation of SU-DHL-6 cells with an IC50 of 0.035 μM [1].		PI3K
T62408	PI3Kδ-IN-11
	PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity. PI3Kδ-IN-11 can be used in B- or T-cell-associated malignancy studies.
T78568	PI3Kδ-IN-15		PI3K
	PI3Kδ-IN-15 (compound 6b) is a potent and selective inhibitor of PI3Kδ, exhibiting an IC50 of 0.5 nM for p110δ and demonstrating over 30-fold selectivity compared to PI3K isoforms γ, β, and α [1].		PI3K
T79627	PI3Kδ-IN-13		PI3K
	PI3Kδ-IN-13 (compound 89), with an IC50 value of 2.6 nM, is an inhibitor of PI3Kδ, applicable for researching diseases involving cell proliferation, including cancer, infection, inflammation, and autoimmune disorders [1]...		PI3K
T63497	PI3Kδ/γ-IN-1
	PI3Kδ/γ-IN-1 is a selective and effective inhibitor of PI3Kδ/γ that can be used in the treatment of hematologic malignancies.
T63221	PI3Kδ/γ-IN-2
	PI3Kδ/γ-IN-2 is a potent, orally bioavailable dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 4.3 nM) with potential for use in anti-B-cell malignancy studies.