Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 38.00 | |
100 mg | In stock | $ 51.00 | |
200 mg | In stock | $ 79.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 47.00 |
Description | Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation. |
Targets&IC50 | ATP systhesis:0.88 μM(Ki) |
In vivo | Fenbufen and its metabolites could be involved in mitochondrial toxicity through inhibition of ATP synthesis[1]. Fenbufen inhibited prostaglandin release by 80% and reduced rates of protein synthesis in normal muscle and in muscle undergoing hypertrophy in response to tenotomy of a synergist[3]. |
Synonyms | CL-82204, Lederfen |
Molecular Weight | 254.28 |
Formula | C16H14O3 |
CAS No. | 36330-85-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 47 mg/mL (184.8 mM)
DMSO: 47 mg/mL (184.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Fenbufen 36330-85-5 Apoptosis Immunology/Inflammation Membrane transporter/Ion channel Neuroscience Proteases/Proteasome Caspase COX ATPase anti-inflammatory tendinitis analgetic Inhibitor inhibit CL 82204 antipyretic ankylosing spondylitis CL-82204 antirheumatic Lederfen osteoarthritis CL82204 Cyclooxygenase inhibitor