Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.
Description | Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation. |
Targets&IC50 | ATP systhesis:0.88 μM(Ki) |
In vivo | Fenbufen and its metabolites could be involved in mitochondrial toxicity through inhibition of ATP synthesis[1]. Fenbufen inhibited prostaglandin release by 80% and reduced rates of protein synthesis in normal muscle and in muscle undergoing hypertrophy in response to tenotomy of a synergist[3]. |
Synonyms | 芬布芬, CL-82204, Lederfen |
Molecular Weight | 254.285 |
Formula | C16H14O3 |
CAS No. | 36330-85-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Ethanol: 47 mg/mL (184.8 mM)
DMSO: 47 mg/mL (184.8 mM)
H2O: <1 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Fenbufen 36330-85-5 蛋白酶体 凋亡 离子通道 免疫与炎症 神经科学 ATPase Caspase COX anti-inflammatory tendinitis CL-82204 Lederfen analgetic CL82204 Inhibitor inhibit CL 82204 antipyretic ankylosing spondylitis antirheumatic osteoarthritis Cyclooxygenase inhibitor