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Fenbufen

Catalog No. T0859   CAS 36330-85-5
Synonyms: CL-82204, Lederfen

Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.

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Fenbufen Chemical Structure
Fenbufen, CAS 36330-85-5
Pack Size Availability Price/USD Quantity
50 mg In stock $ 38.00
100 mg In stock $ 51.00
200 mg In stock $ 79.00
1 mL * 10 mM (in DMSO) In stock $ 47.00
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Purity: 98.35%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.
Targets&IC50 ATP systhesis:0.88 μM(Ki)
In vivo Fenbufen and its metabolites could be involved in mitochondrial toxicity through inhibition of ATP synthesis[1]. Fenbufen inhibited prostaglandin release by 80% and reduced rates of protein synthesis in normal muscle and in muscle undergoing hypertrophy in response to tenotomy of a synergist[3].
Synonyms CL-82204, Lederfen
Molecular Weight 254.28
Formula C16H14O3
CAS No. 36330-85-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 47 mg/mL (184.8 mM)

DMSO: 47 mg/mL (184.8 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

TargetMolReferences and Literature

1. Syed M, et al. Toxicol In Vitro. 2016, 31:23-29. 2. Naora K, et al. J Antimicrob Chemother. 1992, 30(5):673-683. 3. Palmer RM, et al. Br J Pharmacol. 1990, 101(4):835-838.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Protease Inhibitor Library Ion Channel Inhibitor Library Drug-Fragment Library Pyroptosis Compound Library Approved Drug Library Inhibitor Library Immunology/Inflammation Compound Library Anti-Aging Compound Library

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Keywords

Fenbufen 36330-85-5 Apoptosis Immunology/Inflammation Membrane transporter/Ion channel Neuroscience Proteases/Proteasome Caspase COX ATPase anti-inflammatory tendinitis analgetic Inhibitor inhibit CL 82204 antipyretic ankylosing spondylitis CL-82204 antirheumatic Lederfen osteoarthritis CL82204 Cyclooxygenase inhibitor

 

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