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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
p38 MAPK
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
JAK
Caspase
Prostaglandin Receptor
Src
Parasite
NO Synthase
Adenosine Receptor
ERK
FLT
Opioid Receptor
Akt
ROS
PKC
PDGFR
Estrogen Receptor/ERR
MMP
GSK-3
RAAS
TLR
FGFR
Raf
c-Met/HGFR
c-Kit
CDK
TNF
TGF-beta/Smad
COX
Cannabinoid Receptor
Bcr-Abl
HSP
ATPase
ALK
Wnt/beta-catenin
Cytochromes P450
PKA
P-gp
LPL Receptor
NMDAR
Reactive Oxygen Species
Interleukin
Estrogen/progestogen Receptor
Kras
HIV Protease
Serotonin Transporter
Aurora Kinase
Antibiotic
CCR
ROCK
STAT
Tyrosine Kinases
CXCR
Integrin
IGF-1R
PI3K
Drug Metabolite
Neurokinin receptor
Casein Kinase
S1P Receptor
Proton pump
P2X Receptor
Sigma receptor
Antifungal
Trk receptor
DNA/RNA Synthesis
c-RET
FAK
IL Receptor
Hedgehog/Smoothened
SARS-CoV
TAM Receptor
Influenza Virus
PPAR
Angiotensin-converting Enzyme (ACE)
JNK
PDE
c-Fms
Norepinephrine
Virus Protease
CFTR
Ferroptosis
HER
transporter
mTOR
Chloride channel
Bcl-2 Family
Syk
Cysteine Protease
AMPK
Protease-activated Receptor
Beta Amyloid
Endothelin Receptor
Leukotriene Receptor
Cholecystokinin Receptor
Glucagon Receptor
Epigenetic Reader Domain
P2Y Receptor
Mitophagy
PARP
cAMP
SGLT
DYRK
Melanocortin Receptor
ROS Kinase
LPA Receptor
MEK
Anti-infection
Smo
Antioxidant
OX Receptor
Neuropeptide Y Receptor
S6 Kinase
MRP
NOS
Guanylate cyclase
Vasopressin Receptor
Lipoxygenase
BTK
Bradykinin Receptor
CaMK
Tyrosinase
GNRH Receptor
Mitochondrial Metabolism
GPCR19
Phospholipase
ABC Transporter
HSV
GTPase
Rho
Ephrin Receptor
MAPK
HDAC
HCV Protease
Adenylate cyclase
Monoamine Transporter
Arrestin
Monoamine Oxidase
Serine Protease
HIF/HIF Prolyl-Hydroxylase
CSF-1R
PERK
Phosphatase
Nrf2
Neurotensin Receptor
BCRP
CaSR
Dehydrogenase
Immunology/Inflammation related
PAFR
Monocarboxylate transporter
Serine/threonin kinase
Somatostatin
Discoidin Domain Receptor (DDR)
Microtubule Associated
GHSR
GRK
Antiviral
IκB/IKK
Melatonin Receptor
Antifection
PGE Synthase
MAO
Glucocorticoid Receptor
Bombesin Receptor
OAT
Tie-2
Na+/Ca2+ Exchanger
MDM-2/p53
OCT
Apelin receptor
Carbonic Anhydrase
HBV
Sirtuin
FXR
Topoisomerase
PYK2
CRFR
NOD-like Receptor (NLR)
Glucosidase
Beta-Secretase
Nucleoside Antimetabolite/Analog
CGRP Receptor
MLK
RIP kinase
Oxytocin Receptor
Pim
Annexin A
MT Receptor
Chk
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
Acyltransferase
LTR
TSH Receptor
Hydroxylase
CRM1
Glutaminase
Transferase
BACE
DNA Methyltransferase
Thrombin
RSV
Reductase
Myosin
Histone Demethylase
Aryl Hydrocarbon Receptor
p53
Fatty Acid Synthase
Androgen Receptor
Aquaporin
HMG-CoA Reductase
Progesterone Receptor
HCN Channel
HIF
IRAK
IFNAR
NADPH
AhR
Gamma-secretase
PLK
Proteasome
NPC1L1
FOXO
PROTACs
FAAH
glycosidase
DNA
Imidazoline Receptor
MyD88
Glutathione Peroxidase
LDL
PTEN
c-Myc
NOD
Hck
Stearoyl-CoA Desaturase (SCD)
ACK1
PDK
SGK
Amino Acids and Derivatives
Thyroid hormone receptor(THR)
VDAC
IAP
Adiponectin Receptor
OXPHOS
Free radical scavengers
Pyroptosis
Survivin
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
Platelet aggregation
YAP
Na-K-Cl cotransporter
Lipid
ROR
Dynamin
DUB
Succinate Receptor 1 (SUCNR1)
Kisspeptin
ribosome
CRISPR/Cas9
Cadherin
MRGPR
LRRK2
Transaminase
UGT
Liver X Receptor
PAI-1
PD-1/PD-L1
Piezo Channel
Necroptosis
IDO
Lipase
Cell Cycle Arrest
LIM Kinase
Glucokinase
HCAR
MNK
Complement System
DHFR
DNA-PK
AAK1
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
IRE1
PACAP
DNA gyrase
STING
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
Antifolate
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Cuproptosis
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
AIM2
MELK
Aromatase
IKZF
RANKL/RANK
Phosphorylase
Telomerase
MicroRNA
Galectin
Haspin Kinase
Orphan Receptor
Protease
Taste receptor
TOPK
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
Adenosine Deaminase
Liposome
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
RAR/RXR
Neuropeptide W
Amylase
FABP
Huntingtin
Acetyl-CoA Carboxylase
FKBP
GPX
PKM
ASBT
Glutaminyl Cyclase
MIF
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
Mdm2
GSNOR
ASCT
NAMPT
Carboxypeptidase
Gap Junction Protein
Lysosomal Autophagy
ADC Cytotoxin
Sodium-dependent phosphate transporter
IGF-2R

Keywords