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Doxepin hydrochloride

Doxepin hydrochloride
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Purity:99.91%
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Doxepin hydrochloride

Catalog No. T1540Cas No. 1229-29-4
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
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Pack SizePrice/USDAvailabilityQuantity
500 mg$42In Stock
1 g$50In Stock
5 g$128In Stock
10 g$158In Stock
1 mL x 10 mM (in DMSO)$46In Stock
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Product Introduction

Bioactivity
Description
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
AliasToruan, Doxepin HCl, Aponal, Novoxapin
Chemical Properties
Molecular Weight315.837
FormulaC19H22ClNO
Cas No.1229-29-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (189.97 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1662 mL15.8310 mL31.6619 mL158.3095 mL
5 mM0.6332 mL3.1662 mL6.3324 mL31.6619 mL
10 mM0.3166 mL1.5831 mL3.1662 mL15.8310 mL
20 mM0.1583 mL0.7915 mL1.5831 mL7.9155 mL
50 mM0.0633 mL0.3166 mL0.6332 mL3.1662 mL
100 mM0.0317 mL0.1583 mL0.3166 mL1.5831 mL

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