Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 455.00 | |
50 mg | In stock | $ 672.00 | |
100 mg | In stock | $ 956.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 177.00 |
Description | DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines. |
Synonyms | DM1-SSMe |
Molecular Weight | 784.38 |
Formula | C36H50ClN3O10S2 |
CAS No. | 138148-68-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: Soluble
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DM1-SMe 138148-68-2 Cytoskeletal Signaling Microtubule Associated Microtubule/Tubulin ADC Payload anti-tumor activity tumor cell DM1 SMe inhibit Inhibitor maytansinoid ADC Cytotoxin DM-1-SMe antibody-drug conjugate DM1-SSMe DM1SMe inhibitor