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Tubulin inhibitor 6

Name: Tubulin inhibitor 6
Brand: TargetMol
SKU: T13224
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13224Cas No. 105925-39-1

Alias iHAP1

Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.

Tubulin inhibitor 6

🥰Excellent

Purity: 99.05%

Catalog No. T13224Alias iHAP1Cas No. 105925-39-1

Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$51	In Stock
25 mg	$83	In Stock
50 mg	$125	In Stock
100 mg	$190	In Stock
500 mg	$455	In Stock
1 mL x 10 mM (in DMSO)	$33	In Stock

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Batch Information

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Purity:99.05%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.
Targets&IC50	Tubulin polymerization:0.87 μM (IC50)
In vitro	Tubulin inhibitor 6 exhibits submicromolar antiproliferative activity.
Synonyms	iHAP1

Chemical Properties

Molecular Weight	367.85
Formula	C₂₀H₁₄ClNO₂S
Cas No.	105925-39-1
Smiles	COc1ccc(cc1)C(=O)N1c2ccccc2Sc2ccc(Cl)cc12
Relative Density.	1.364 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (108.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7185 mL	13.5925 mL	27.1850 mL	135.9250 mL
5 mM	0.5437 mL	2.7185 mL	5.4370 mL	27.1850 mL
10 mM	0.2718 mL	1.3592 mL	2.7185 mL	13.5925 mL
20 mM	0.1359 mL	0.6796 mL	1.3592 mL	6.7962 mL
50 mM	0.0544 mL	0.2718 mL	0.5437 mL	2.7185 mL
100 mM	0.0272 mL	0.1359 mL	0.2718 mL	1.3592 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc