Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DC-S239 (DC-S239) is a selective inhibitor of histone methyltransferase SETD7 (IC50 = 4.59 μM) with anticancer activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 | |
500 mg | In stock | $ 2,570.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 259.00 |
Description | DC-S239 (DC-S239) is a selective inhibitor of histone methyltransferase SETD7 (IC50 = 4.59 μM) with anticancer activity. |
In vitro | DC-S239 (0-100 μM) inhibits the proliferation of MCF7, HL60 and MV4-11 cells in a dose-dependent manner with the IC50 values of 10.93 μM and 16.43 μM, respectively. DC-S239 inhibits DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a by less than 45%, whereas it inhibits SET7 by 90% at concentrations of 100 μM[1]. |
Molecular Weight | 349.36 |
Formula | C15H15N3O5S |
CAS No. | 303141-21-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.5 mg/mL (15.74 mM)
You can also refer to dose conversion for different animals. More
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DC-S239 303141-21-1 Chromatin/Epigenetic Histone Methyltransferase Ethyl 2amino4methyl5[(3nitrophenyl)carbamoyl]thiophene3carboxylate MCF7 Ethyl 2 amino 4 methyl 5 [(3 nitrophenyl)carbamoyl]thiophene 3 carboxylate DC-S-239 anti-cancer SET7 inhibitor HL60 inhibit MV4-11 Inhibitor DC-S 239 inhibitor