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TargetMol | Compound Library

Histone Modification Compound Library

Catalog No. L3500

A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs. The TargetMol's Histone Modification Compound Library, a unique collection of 569 histone modification related compounds, can be used for research in histone modification and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3500

Histone Modification Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 569 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Epigenetic Reader Domain
Histone Methyltransferase
HDAC
Apoptosis
Sirtuin
Histone Demethylase
Histone Acetyltransferase
Autophagy
PROTACs
HIV Protease
Endogenous Metabolite
Antibacterial
Mitophagy
CDK
Virus Protease
MDM-2/p53
Ligands for Target Protein for PROTAC
JAK
Parasite
DNA/RNA Synthesis
Monoamine Oxidase
NF-κB
PI3K
PDE
Wnt/beta-catenin
TNF
COX
Antiviral
Antifungal
Gamma-secretase
Phosphatase
Histamine Receptor
Interleukin
Adenosine Receptor
c-Myc
ERK
MAO
EGFR
Carboxypeptidase
GABA Receptor
PD-1/PD-L1
Influenza Virus
Dehydrogenase
DNA Methyltransferase
PPAR
MMP
OXPHOS
TLR
Nrf2
p53
RAAS
SARS-CoV
AMPK
Tyrosine Kinases
NR4A
HSV
mTOR
PARP
Bcl-2 Family
Dopamine Receptor
Caspase
Androgen Receptor
Amino Acids and Derivatives
Serine Protease
Immunology/Inflammation related
Mitochondrial Metabolism
Angiotensin-converting Enzyme (ACE)
PLK
HIF/HIF Prolyl-Hydroxylase
MyD88
Topoisomerase
Tyrosinase
DNA-PK
PKA
Glucosidase
Akt
HSP
IκB/IKK
Phospholipase
Antioxidant
HBV
CCR
HER
Mdm2
Ferroptosis
Reactive Oxygen Species
Lipoxygenase
Reverse Transcriptase
Sodium Channel
NOD
Antibiotic
Antifolate
UGT
Bcr-Abl
Fatty Acid Synthase
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Aminopeptidase
Methionine Adenosyltransferase (MAT)
NADPH
PKC
Adrenergic Receptor
IDO
Molecular Glues
Cytochromes P450
Telomerase
PSMA
transporter
Beta Amyloid
STAT
5-HT Receptor
MEK
FLT
BMI-1

Keywords