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TargetMol | Compound Library

Histone Modification Compound Library

Catalog No. L3500

A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs.

The TargetMol's Histone Modification Compound Library, a unique collection of 700 histone modification related compounds, can be used for research in histone modification and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3500

Histone Modification Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 700 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Epigenetic Reader Domain
Histone Methyltransferase
HDAC
Apoptosis
Sirtuin
Histone Demethylase
Histone Acetyltransferase
Autophagy
PROTACs
Endogenous Metabolite
HIV Protease
NF-κB
Antibacterial
Akt
PI3K
MDM-2/p53
Mitophagy
DNA/RNA Synthesis
Ligands for Target Protein for PROTAC
Antifungal
Virus Protease
Parasite
CDK
JAK
COX
GABA Receptor
TNF
Wnt/beta-catenin
Monoamine Oxidase
ERK
PDE
ROS
STAT
AMPK
HIF/HIF Prolyl-Hydroxylase
Adenosine Receptor
RAAS
Histamine Receptor
Phosphatase
PPAR
PARP
Caspase
Gamma-secretase
mTOR
Interleukin
Antiviral
Nrf2
AChR
Dopamine Receptor
p38 MAPK
Dehydrogenase
c-Myc
PKA
Estrogen Receptor/ERR
PKC
MAO
Molecular Glues
Angiotensin-converting Enzyme (ACE)
MMP
EGFR
TLR
Bcl-2 Family
Influenza Virus
Carboxypeptidase
DNA Methyltransferase
Antibiotic
p53
PD-1/PD-L1
Ferroptosis
Antioxidant
HBV
Tyrosine Kinases
Calcium Channel
NR4A
Adrenergic Receptor
UGT
Mitochondrial Metabolism
HSV
Cholinesterase (ChE)
Cytochromes P450
CaMK
Androgen Receptor
OXPHOS
HSP
SARS-CoV
transporter
IκB/IKK
Phospholipase
5-HT Receptor
Potassium Channel
Sodium Channel
Tyrosinase
NOD-like Receptor (NLR)
GPCR
Mdm2
NOS
GDNF
DNA-PK
Integrin
MyD88
Amino Acids and Derivatives
NADPH
JNK
GTPase
MRP
Serine Protease
Antifolate
Serotonin Transporter
Cell Cycle Arrest
TRP/TRPV Channel
IDO
IAP
Immunology/Inflammation related
Topoisomerase
Bcr-Abl
Glucagon Receptor
Phosphorylase
NMDAR
ABC Transporter
Glucosidase
Monoamine Transporter
Reactive Oxygen Species
Fatty Acid Synthase
IL Receptor
CCR
Chk
PAD
cAMP
Lipoxygenase
glycosidase
Norepinephrine
Indoleamine 2,3-Dioxygenase (IDO)
TGF-beta/Smad
Telomerase
PSMA
Survivin
P-gp
Aminopeptidase
Pyroptosis
Casein Kinase
Methionine Adenosyltransferase (MAT)
Beta Amyloid
Reverse Transcriptase
FOXO
PLK
MEK
Cannabinoid Receptor
FLT
BMI-1
NOD
S6 Kinase
HER
NO Synthase

Keywords