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Gambogenic acid

Catalog No. T8201 CAS 173932-75-7

Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.

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Gambogenic acid, CAS 173932-75-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 94.00
5 mg	In stock	$ 219.00
10 mg	In stock	$ 378.00
25 mg	In stock	$ 623.00
50 mg	In stock	$ 882.00
100 mg	In stock	$ 1,180.00
1 mL * 10 mM (in DMSO)	In stock	$ 297.00

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Purity: 99.6%

Purity: 98.36%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.
Source	Natural Products > Clusiaceae > Garcinia

Molecular Weight	630.77
Formula	C38H46O8
CAS No.	173932-75-7

Storage

keep away from direct sunlight,keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (158.53 mM)

References and Literature

1. Wang X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017 May 2;36(9):1243-1260.

Citations

1. Wu J, Wang D, Zhou J, et al. Gambogenic acid induces apoptosis and autophagy through ROS‐mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells. Phytotherapy Research. 2022;1–19.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Cancer Active Compound Library Polyphenolic Natural Product Library Bioactive Compounds Library Max Autophagy Compound Library Methylation Compound Library Covalent Inhibitor Library Traditional Chinese Medicine Monomer Library Anti-Tumor Natural Product Library Bioactive Compound Library

Related Products

Related compounds with same targets

BAY-598 ZLD1039 CPI-1205 CPI-360 Cyproheptadine hydrochloride sesquihydrate Menin-MLL inhibitor MI-2 lutidinic acid EPZ004777 hydrochloride

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Gambogenic acid 173932-75-7 Chromatin/Epigenetic Histone Methyltransferase inhibit Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.