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TargetMol | Compound Library

Ion Channel Targeted Library

Catalog No. L2300

Given the central functional role that the ion channel superfamily plays in human physiology, its membrane localization, and the diverse tissue distribution of different members of the family, it represents an attractive potential target class for drug discovery. Ion channelsplay a fundamental role in the way cells communicate. This communication between cells allows for the orchestration of physical and mental activities in humans. A number of diseases occur when ion channels do not function properly. Some examples are diabetes, neuropathic pain, cardiovascular diseases, asthma, epilepsy, and neurodegenerative disease, etc.

The Ion Channel Inhibitor Library by TargetMol, containing 1220 compounds targeting ion channels, can be used for research in ion channel, high throughput screening and high content screening for ion channel drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2300

Ion Channel Targeted Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1220 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Targets include potassium channel, calcium channel, sodium channel, Proton pump, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Calcium Channel
Potassium Channel
Sodium Channel
GABA Receptor
TRP/TRPV Channel
AChR
iGluR
Apoptosis
Autophagy
Endogenous Metabolite
NMDAR
P2X Receptor
Parasite
Antibacterial
NF-κB
5-HT Receptor
Chloride channel
ROS
GluR
COX
Dopamine Receptor
ERK
Cytochromes P450
Adrenergic Receptor
Histamine Receptor
Reactive Oxygen Species
ATPase
Akt
EGFR
HIV Protease
Caspase
p38 MAPK
Drug Metabolite
P-gp
Anti-infection
NO Synthase
PPAR
Interleukin
DNA/RNA Synthesis
TNF
Antibiotic
Ferroptosis
PI3K
mTOR
Cannabinoid Receptor
Antifungal
JNK
HCN Channel
Cholinesterase (ChE)
CaMK
SARS-CoV
Beta Amyloid
STAT
GPCR
Proton pump
Na+/Ca2+ Exchanger
Virus Protease
PKC
PDE
Mitochondrial Metabolism
Influenza Virus
Carbonic Anhydrase
Dehydrogenase
Antioxidant
PERK
Mitophagy
MRP
PKA
Wnt/beta-catenin
VDAC
Topoisomerase
ABC Transporter
Lipoxygenase
TLR
MEK
VEGFR
Monoamine Transporter
IL Receptor
Bcl-2 Family
Nrf2
HDAC
AMPK
Transaminase
NADPH
RAAS
Serine/threonin kinase
LDL
Gamma-secretase
MMP
Norepinephrine
TGF-beta/Smad
transporter
GluCls
Phospholipase
HMG-CoA Reductase
Sigma receptor
Tyrosinase
Microtubule Associated
Monoamine Oxidase
NOS
Piezo Channel
HCV Protease
Integrin
Amino Acids and Derivatives
Phosphatase
GSK-3
PARP
Serine Protease
ROCK
Glucocorticoid Receptor
PAFR
MT Receptor
GlyT
Na-K-Cl cotransporter
Antifection
Opioid Receptor
HSV
cAMP
IGF-1R
BCRP
Beta-Secretase
Prostaglandin Receptor
Trk receptor
GPCR19
Sirtuin
PAI-1
IκB/IKK
DNA Methyltransferase
Thrombin
AhR
CFTR
Melanin-concentrating Hormone Receptor (MCHR)
Proteasome
Taste receptor
MicroRNA
Monocarboxylate transporter
ASBT
Histone Methyltransferase
Src
c-Met/HGFR
LPL Receptor
LTR
Arrestin
Reductase
Necroptosis
Glutathione Peroxidase
Melatonin Receptor
OCT
c-Myc
N-Acetylglucosaminyltransferase
CaSR
Estrogen Receptor/ERR
Serotonin Transporter
Nucleoside Antimetabolite/Analog
Leukotriene Receptor
FXR
Glutaminase
MAO
Aryl Hydrocarbon Receptor
CSF-1R
Myosin
RIP kinase
UGT
CDK
Glucagon Receptor
DNA gyrase
Glucosidase
Anion Exchanger
Molecular Glues
JAK
PAK
CCR
CXCR
Angiotensin-converting Enzyme (ACE)
PTEN
Epigenetic Reader Domain
glycosidase
DNA
Androgen Receptor
Lipid
Acyltransferase
HSP
STING
LRRK2
AIM2
Pyroptosis
RSV
GST
c-Fms
FOXO
FGFR
CGRP Receptor
MDM-2/p53
Gap Junction Protein
Platelet aggregation
NOD
IRAK
Ras
Protease-activated Receptor
ROS Kinase
NOD-like Receptor (NLR)
PKM
S1P Receptor
Sodium-dependent phosphate transporter

Keywords