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Bevenopran

Bevenopran
Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
Catalog No. T14551Cas No. 676500-67-7
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Purity:98.76%
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Bevenopran

Catalog No. T14551Cas No. 676500-67-7
Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$98In Stock
5 mg$232In Stock
10 mg$346In Stock
25 mg$555In Stock
50 mg$756In Stock
100 mg$987In Stock
500 mg$1,980In Stock
1 mL x 10 mM (in DMSO)$256In Stock
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Product Introduction

Bioactivity
Description
Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
In vivo
Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].
AliasCB-5945, ADL-5945
Chemical Properties
Molecular Weight386.44
FormulaC20H26N4O4
Cas No.676500-67-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (310.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5877 mL12.9386 mL25.8772 mL129.3862 mL
5 mM0.5175 mL2.5877 mL5.1754 mL25.8772 mL
10 mM0.2588 mL1.2939 mL2.5877 mL12.9386 mL
20 mM0.1294 mL0.6469 mL1.2939 mL6.4693 mL
50 mM0.0518 mL0.2588 mL0.5175 mL2.5877 mL
100 mM0.0259 mL0.1294 mL0.2588 mL1.2939 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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