Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 155.00 | |
5 mg | In stock | $ 473.00 | |
10 mg | In stock | $ 679.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 |
Description | Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line. |
In vitro | In this study, we found that two sesquiterpene lactones, isobutyroylplenolin and Arnicolide D, from Centipeda minima L. (Compositae) exerted stronger cytotoxic activity than cisplatin on the human colon carcinoma HT-29 cell line. Furthermore, the cytotoxicity of these two compounds on normal cells was weaker than that of cisplatin. |
Source |
Molecular Weight | 332.39 |
Formula | C19H24O5 |
CAS No. | 34532-68-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.75 mg/mL (8.27 mM)
You can also refer to dose conversion for different animals. More
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Arnicolide D 34532-68-8 Apoptosis Cytoskeletal Signaling JAK/STAT signaling PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Akt Caspase PI3K STAT mTOR Mammalian target of Rapamycin Phosphoinositide 3-kinase inhibit Inhibitor PKB Protein kinase B inhibitor