Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Alizarin (Mordant Red 11), a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 μM), CYP1A2 (IC50 =10.0 μM )and CYP1B1(IC50 = 2.7 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 46.00 | |
1 g | In stock | $ 55.00 | |
5 g | In stock | $ 73.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Alizarin (Mordant Red 11), a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 μM), CYP1A2 (IC50 =10.0 μM )and CYP1B1(IC50 = 2.7 μM). |
Targets&IC50 | CYP1A1:6.2 μM, CYP1A2:10.0 μM, CYP1B1:2.7 μM |
In vitro | Within the bodies of poisoned animals, Alizarin has been shown to reduce the levels of hepatic mercapturic acid conjugates and serum alanine transaminase (ALT) levels. |
In vivo | In rat liver microsomes, Alizarin can inhibit the oxidation of phenoxy radicals, superoxide anion radicals, and lipid peroxides. |
Source |
Synonyms | Mordant Red 11, Anthraquinonic |
Molecular Weight | 240.21 |
Formula | C14H8O4 |
CAS No. | 72-48-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (187.3 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Alizarin 72-48-0 Metabolism P450 Inhibitor inhibit Mordant Red 11 Anthraquinonic inhibitor