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8-Hydroxyguanosine

Catalog No. TQ0154 CAS 3868-31-3

8-hydroxyguanosine (8-OHG) is a marker for measuring the rate of oxidative damage to nucleic acids and lipids.

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8-Hydroxyguanosine, CAS 3868-31-3

Pack Size	Availability	Price/USD
2 mg	In stock	$ 37.00
5 mg	In stock	$ 61.00
10 mg	In stock	$ 97.00
25 mg	In stock	$ 194.00
50 mg	In stock	$ 311.00
1 mL * 10 mM (in DMSO)	In stock	$ 68.00

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Purity: 99.67%

Purity: 96.67%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	8-hydroxyguanosine (8-OHG) is a marker for measuring the rate of oxidative damage to nucleic acids and lipids.
In vivo	The concentration of 8-OHG in CSF in Parkinson's disease (PD) patients is approximately three-fold that in controls. The concentration of 8-OHG in CSF decreased significantly with the duration of disease. However, the concentration of 8-OHG in serum was not significantly altered in PD patients compared to that in controls.

Molecular Weight	299.24
Formula	C10H13N5O6
CAS No.	3868-31-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 240 mg/mL (802.03 mM)

References and Literature

1. Harman SM, et al. Urinary excretion of three nucleic acid oxidation adducts and isoprostane F(2)alpha measured by liquid chromatography-mass spectrometry in smokers, ex-smokers, and nonsmokers. Free Radic Biol Med. 2003 Nov 15;35(10):1301-9. 2. Abe T, et al. Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease. Neurosci Lett. 2003 Jan 16;336(2):105-8.

Related compound libraries

This product is contained In the following compound libraries：

Human Endogenous Metabolite Library Human Metabolite Library Natural Product Library for HTS Nucleotide Compound Library Bioactive Compounds Library Max Human Endogenous Metabolite Compound Library Plus NO PAINS Compound Library Bioactive Compound Library Bioactive Lipid Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

8-Hydroxyguanosine 3868-31-3 Metabolism Others Endogenous Metabolite 8 Hydroxyguanosine Inhibitor 8Hydroxyguanosine inhibit inhibitor

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