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3-Bromopyruvic acid

Catalog No. T5882   CAS 1113-59-3
Synonyms: Bromopyruvic acid, Hexokinase II Inhibitor II, 3-BP
Purity 95.00% Datasheet

3-Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.

3-Bromopyruvic acid, CAS 1113-59-3
Pack Size Availability Price/USD Quantity
10 mg In stock 18.00
25 mg In stock 26.00
50 mg In stock 35.00
100 mg In stock 42.00
200 mg In stock 50.00
500 mg In stock 60.00
1 g In stock 69.00
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Purity 95.00%
Purity 95.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description 3-Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
Targets&IC50 hexokinase II :ic50 2.4 mM (Ki),  
Synonyms Bromopyruvic acid, Hexokinase II Inhibitor II, 3-BP
Purity 95.00%
Appearance solid
Molecular Weight 166.96
Formula C3H3BrO3
CAS No. 1113-59-3

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

H2O: 32 mg/mL (191.66 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Leng X , Peng J , Yu X , et al. 3-Bromopyruvic Acid, A Hexokinase II Inhibitor, is an Effective Antitumor Agent on the Hepatoma Cells : in vitro and in vivo Findings[J]. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), 2014, 14(5):-. 2. Sadowska-Bartosz I, et al. Anticancer agent 3-bromopyruvic acid forms a conjugate with glutathione. Pharmacol Rep. 2016 Apr;68(2):502-5.

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