stabilized — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19235	CHAPS		Others
	CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.		Others
T32781	Lipofundin S	Phospholipid - stabilized soybean oil,Intralipid,Intralipid 20,Medialipid,Lipofundin S 10
	Lipofundin S is an emulsion containing soybean oil, glycerol, and soy phosphatides.
T17203	UNC0224		Histone Methyltransferase
	UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.		Histone Methyltransferase
T7966	3-O-Ethyl-L-ascorbic acid		Tyrosinase
	3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative. It also has antioxidant properties.		Tyrosinase
T39508	KY-02327		Others
	KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differenti...		Others
T75319	Taurodeoxycholic acid	Taurodeoxychloic acid	Apoptosis , Calcium Channel , Caspase
	Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic a...		Apoptosis , Calcium Channel , Caspase
T32589	Laudanidine	Tritopin,Tritopine,L-Laudanine
	Laudanidine is a nitrile-stabilized ammonium ylide.
T34457	RX 783030	RX783030,RX-783030
	RX 783030 is an enkephalin analog that is stabilized.
TP2117	SAHM1
	Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.
T24639	PIH	pyrimidine-indole hybrid
	PIH is a ciliogenesis inhibitor by microtubule destabilization that acts by antagonizing Hh signaling by repressing cilia biogenesis and disassembly of alpha-tubulin in its stabilized form.
T11059	DM4-SMe		Others
	DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds ...		Others
T68686	DAP-81
	DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50...
T69998	DG046
	DG046 is a novel potent phosphinic pseudopeptide ERAP1 inhibitor, binding in the ERAP1 active site, being stabilized by an unusual extensive network of π-stacking interactions
T76694	Odronextamab
	Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].
T27210	DRX-065	DRX 065,DRX065,deuterated R-enantiomer of pioglitazone
	DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects,...
T18722	MAC glucuronide α-hydroxy lactone-linked SN-38		Others
	MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a cytotoxic drug linker that maintains a stabilized lactone form, showing efficacy against L540cy and Ramos cells, with IC50 values of 99 and ...		Others
TP1546	HIF-1 alpha (556-574) TFA (1201633-99-9 free base)	HIF-1 alpha (556-574) TFA
	This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in resp...
T80078	Calciseptin		Calcium Channel
	Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It specifically targets and blocks L-type calcium channels [1...		Calcium Channel
TP2301	Type II collagen fragment		Others
	Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primar...		Others
T80454	BmK-M1		Sodium Channel
	BmK-M1, a scorpion-derived toxin, consists of a 64-amino acid polypeptide stabilized by four disulfide bridges. This compound functions as an inhibitor of the Na+ channel, classifying it as both a cardiotoxin and a neuro...		Sodium Channel