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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4726 | D-Glucose 6-phosphate sodium | G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate | Others , Endogenous Metabolite |
In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at t... | |||
T3244 | 2-Deoxy-2-sulfoamino-D-glucose sodium | N-Sulfo-D-glucosamine sodium salt,N-Sulfo-glucosamine sodium salt,GlcN-2S,2-Deoxy-2-sulfamino-D-glucopyranose | Others , Endogenous Metabolite |
2-Deoxy-2-sulfoamino-D-glucose sodium (GlcN-2S) is possible to effect reaction at arthritis. | |||
T37118 | ADP-Glucose (sodium salt) | ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt) | |
ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria.... | |||
T37899 | UDP-β-D-Glucose (sodium salt) | ||
UDP-β-D-Glucose is the stereoisomer of UDP-α-D-glucose (sodium salt) . The activities of the UDP-β-D-glucose isomer are not known. | |||
T37898 | UDP-α-D-Glucose (sodium salt hydrate) | ||
UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14receptor (EC50= 0.35 μM), an atypical P2Y receptor involved in the activation ... | |||
T37786 | 1-thio-β-D-Glucose (sodium salt) | ||
1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position. The thiol group allows diverse chemical reactions, including click chemistry and polymerization. 1-thio-β-D-... | |||
T35416 | α-D-Glucose-1-phosphate (sodium salt hydrate) | ||
α-D-Glucose-1-phosphate is an intermediate in glycogen metabolism.1,2It is a precursor in the biosynthesis of UDP-glucose, the glucose donor in glycogen biosynthesis.2α-D-Glucose-1-phosphate can be formed during glycogen... | |||
T4743 | Uridine 5′-diphosphoglucose disodium salt | UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal | Endogenous Metabolite , P2Y Receptor |
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in Metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM). It c... | |||
T38843 | Enavogliflozin | DWP-16001 | SGLT |
Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor. | |||
T7717 | Sodium 2-oxopropanoate | Sodium pyruvate | Reactive Oxygen Species , Endogenous Metabolite |
Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease. | |||
T31976 | Glymidine sodium | Others | |
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion. | |||
T15656 | KGA-2727 | SGLT | |
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA... | |||
T9590 | T-1095 | SGLT , transporter | |
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2). | |||
T2385 | Ipragliflozin | ASP1941 | SGLT |
Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. | |||
T1766 | Empagliflozin | BI 10773 | SGLT |
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes. | |||
T2389 | Dapagliflozin | BMS-512148 | SGLT , HIF |
Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. | |||
T2924 | Phloretin | Dihydronaringenin,NSC 407292,RJC 02792 | SGLT , transporter , Endogenous Metabolite |
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav... | |||
T2922 | Phlorizin | Floridzin,NSC 2833,Phloridzin | ATPase , SGLT |
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) . | |||
T3547 | Sotagliflozin | LX-4211,LP-802034 | SGLT |
Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglycemic activity. | |||
T4999 | Ertugliflozin | MK-8835,PF-04971729 | SGLT |
PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). |