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Catalog No. T2385   CAS 761423-87-4
Synonyms: ASP1941

Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.

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Ipragliflozin Chemical Structure
Ipragliflozin, CAS 761423-87-4
Pack Size Availability Price/USD Quantity
25 mg In stock $ 52.00
50 mg In stock $ 84.00
100 mg In stock $ 137.00
200 mg In stock $ 218.00
500 mg In stock $ 462.00
1 mL * 10 mM (in DMSO) In stock $ 48.00
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Purity: 99.97%
Purity: 99.37%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Targets&IC50 mouse SGLT2:5.64 nM, hSGLT2:7.4 nM, rat SGLT2:6.73 nM
Kinase Assay Inhibition of TNF-α synthesis: TNF-α inhibitory activity is measured in lipopolysacharide (LPS) stimulated PBMC. Pomalidomide is added to human PBMCs 1 hour prior to the addition of LPS (1 μg/mL) and incubation continued for an additional 18-20 hours. Supernatants are then harvested, and the concentration of TNF-α in the supernatants is determined by ELISA. The concentration of Pomalidomide that inhibits TNF- production by 50% (IC50) is calculated by nonlinear regression analysis. The human whole blood TNF- inhibition assay is run in a similar fashion to the PBMC assay except that heparinized fresh human whole blood is plated directly into microtiter plates.
Synonyms ASP1941
Molecular Weight 404.45
Formula C21H21FO5S
CAS No. 761423-87-4


Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 70 mg/mL (173.07 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Imamura M, et al. Bioorg Med Chem. 2012 May 15;20(10):3263-79.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Clinical Compound Library Highly Selective Inhibitor Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Anti-Diabetic Compound Library Orally Active Compound Library Target-Focused Phenotypic Screening Library FDA-Approved & Pharmacopeia Drug Library Approved Drug Library

Related Products

Related compounds with same targets
SGLT inhibitor-1 SGL5213 Licogliflozin Picraline LY2794193 IRAK inhibitor 4 trans HSK0935 Kushenol C

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Ipragliflozin 761423-87-4 GPCR/G Protein SGLT Inhibitor ASP1941 ASP 1941 Sodium-dependent glucose cotransporters inhibit ASP-1941 inhibitor