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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12909 | SID 26681509 | Cysteine Protease , Parasite | |
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM). | |||
T0378 | Oxybuprocaine hydrochloride | Risedronic Acid,Oxybuprocaine HCl | Sodium Channel |
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology. | |||
T13048 | SynuClean-D | SC-D | Others |
SynuClean-D (SC-D) is an α-synuclein aggregation inhibitor preventing fibril propagation, disrupting mature amyloid fibrils, and abolishing the degeneration of dopaminergic neurons in an animal model of Parkinson’s disea... | |||
T0802 | Procaine hydrochloride | Novocaine HCl,Procaine HCl | Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR |
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... | |||
T35141 | WW-781 | WW 781,NK 2935 | |
WW-781 is used to measure action potential propagation in the heart. | |||
T71191 | Covidcil-19 | ||
Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency i... | |||
T75331 | Brilliant green | ||
Brilliant green, a cationic dye, is utilized for coloring silk and wool. Additionally, it halts the propagation of mold, intestinal parasites, and fungus, proving effective against Gram-positive bacteria [1] [2]. | |||
T70971 | VGD020 | ||
VGD020 is a CD4 and sortilin inhibitor. It displayed activity for sortilin down-modulation and reduction of progranulin-induced breast cancer stem cell propagation. | |||
T36910 | PF 04449913 maleate | ||
Potent Smo antagonist (IC50 = 5 nM). Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model. Also eliminates self-propagation capacity of AML cells. Munchhof et al (2011) Discov... | |||
T74866 | Antibacterial agent 116 | ||
Antibacterial agent 116, a benzophenone-containing salicylanilide compound, exhibits potent antibacterial activity by inhibiting peptidoglycan formation. It is employed as a photoaffinity probe to label Acinetobacter bau... | |||
T75152 | ARC19499 | ||
ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor... | |||
T63831 | SID 26681509 quarterhydrate | ||
SID 26681509 quarterhydrate is a reversible, potent, selective, competitive inhibitor of human cathepsin L (IC50: 56 nM). SID 26681509 inhibits in vitro propagation of Plasmodium falciparum (IC50: 15.4 μM) and inhibits L... | |||
T78060 | ProTx II TFA | Sodium Channel | |
ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductan... | |||
T7911 | Arbidol | ||
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir both suppresses virus propagation and modulates the expression of inf... | |||
T23210 | Quinacrine (dihydrochloride hydrate) | Quinacrine (hydrochloride hydrate) (83-89-6 free base) | Others |
Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM) and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of pr... | |||
T38142 | Phosphatidylethanolamines (soy) | ||
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholi... |