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Search Results for " p42/p44 "

7

Compounds

Cat No. Product Name Synonyms Targets
T2026 CYM5442 S1P Receptor , LPL Receptor
CYM5442 is an S1P agonist, targeting to Sphingosine.
T4092 AG126 Tyrphostin AG126,AG 126 ERK , COX
AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expres...
T4431 Olodanrigan PD-126055,EMA401 RAAS
Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA...
T6108 Ki16425 Debio 0719 LPA Receptor , LPL Receptor
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
T41144 CYM5442 hydrochloride CYM 5442 hydrochloride
CYM 5442 hydrochloride is a potent and selective S1P1agonistin vitro(EC50 = 1.35 nM). Activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. Induces acute lymphopenia in mice. Brain p...
T13679 Enniatin B ERK
Enniatins B decreases the activation of ERK (p44/p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 113 μM in an enzyme assay using rat liv...
T13680 Enniatin B1 ERK
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier, decreases the activation of ERK (p44/p42), and inhibits moderately TNF-α-induced NF-κB activation. Furthermore, it inhibits acyl-CoA: cholesterol acyltr...
TargetMol