20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15545 | ICA-27243 | Potassium Channel | |
ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-27243 also has antiepileptic and anticonvulsant effects. | |||
T26086 | Rilmakalim | Sodium Channel | |
Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect. | |||
T23563 | ZM 226600 | Potassium Channel | |
ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity. | |||
T90604 | PCO 400 | ||
PCO 400 is an analog of comakalim that acts as a selective and potent ATP-sensitive K+ channel opener. | |||
T7612 | ICA 110381 | Potassium Channel | |
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy | |||
T24786 | SG-209 | ||
SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator. | |||
T4294 | NS 11021 | NS11021 | Potassium Channel |
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels | |||
T6504 | Flupirtine maleate | Katadolon maleate | Potassium Channel , NMDAR , iGluR |
Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener. | |||
T26086L | 1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one | Others | |
1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one is an isomer of Rilmakalim, a potassium channel opener (PCO), which can activate ATP-sensitive K+ channels in the heart or other tissues | |||
T27624 | Iptakalim Hydrochloride | Potassium Channel , AChR | |
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2... | |||
T17269 | Y-27152 | Others | |
Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener. | |||
T35311 | ZM 260384 | ZM260384,ZM-260384 | |
ZM 260384 is a potassium channel opener. | |||
T16267 | Naminidil | BMS 234303-01 | Others |
Naminidil is an opener of cyanoguanidine KATP. | |||
T28583 | Ro 31-7837 | Ro-31-7837,Ro 317837 | |
Ro 31-7837 is an opener of potassium channel. | |||
T28134 | NC00075159 | NC 00075159,NC-00075159 | |
NC00075159 is an opener of human KCNQ4 (Kv7.4) potassium channel. | |||
T13949 | U89232 | Others | |
U-89232 is an opener of the cardioselective KATP channel. | |||
T30487 | BMS 180448 | BMS-180448,BMS180448 | |
BMS 180448 is a prototype mitochondrial ATP-sensitive K+ (Mitok (ATP)) channel opener with cardioprotective and vasodilating properties. | |||
T28195 | NS004 | NS 004,NS-004 | |
NS004 is a large-conductance K+ channel opener, it inhibits mitochondrial function in glioma cells. | |||
T17268 | Y-26763 | Others | |
Y-26763 is a K+ channel opener and active metabolite of Y-27152. This is an ATP-sensitive K+ (KATP) channel activator. | |||
T25102 | Aprikalim | RP52891,RP-52891,RP 52891 | |
Aprikalim is a specific and selective ATP-sensitive K+ (KATP) channel opener. Aprikalim affords cardioprotection and at higher doses also cause peripheral or coronary vasodilatation. |