neurogenic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2711	Chembridge-5861528	TCS 5861528	TRP/TRPV Channel
	Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.		TRP/TRPV Channel
T1092	Zolmitriptan	311C90,BW-311C90	5-HT Receptor
	Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and...		5-HT Receptor
T2547	Droxidopa	SM5688,DOPS,L-DOPS	Adrenergic Receptor
	Droxidopa (L-DOPS) is an orally available prodrug of norepinephrine that is used in the treatment of symptomatic orthostatic hypotension due to neurogenic causes of autonomic failure.		Adrenergic Receptor
T9263	Cim0216	N-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)acetamide	TRP/TRPV Channel
	CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.		TRP/TRPV Channel
T20423	Dibenzylamine	Dibenzyl-amine,N-Benzylbenzylamine,Bibenzylamine,N-benzyl-1-phenylmethanamine,Benzenemethanamine, N-(phenylmethyl)-,AI315327,AI3-15327,AI3 15327	Others
	Dibenzylamine (N-Benzylbenzylamine) is a part of potent neurogenic agent.		Others
TN5757	P-Hydroxybenzaldehyde glucoside	4-formylphenyl b-d-glucopyranoside,Gastrodin Impurity
	p-Hydroxybenzaldehyde glucoside (4-formylphenyl b-d-glucopyranoside) is an inhibitory aspergillus derivative with analgesic activity and can be used to study neurogenic pain.
T1833	NSI189	NSI-189,NSI 189	Others
	NSI189 (NSI-189) is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.		Others
T21244	NSI-189 Phosphate	NSI189 Phosphate,NSI 189 Phosphate	Others
	NSI-189 Phosphate is a novel neurogenic molecule with pleiotropic properties, including antidepressant, procognitive, synaptoplastic, and neurotrophic activities demonstrated in preclinical studies. Its antidepressant ac...		Others
T10012	P7C3-OMe		Others
	P7C3-OMe, a pro-neurogenic agent, has therapeutic benefits in neurodegenerative diseases. The R-enantiomer of P7C3-OMe is far more active than the S-enantiomer.		Others
T25615	Lanepitant	LY303870,LY-303870,LY 303870	Others
	Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.		Others
T1993	J-147	J147	Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
	J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T25616	Lanepitant 2HCl	LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride	Neurokinin receptor
	Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam...		Neurokinin receptor
TN6872	Trypsin		Protease-activated Receptor
	Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...		Protease-activated Receptor
T7825	Distigmine Bromide	BC 51,Ubretid,BC51,Hexamarium,BC-51
	Distigmine Bromide is an acetylcholinesterase inhibitor. It is used for the treatment of underactive neurogenic bladder and myasthenia gravis.
T33652	Neurodazole
	Neurodazole is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons.
T3290L	Pikamilone Sodium	GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na
	Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.
T27915	LY 302148	LY-302148,LY302148
	LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.
T25617	Lanepitant HCl trihydrate	Lanepitant dihydrochloride trihydrate
	Lanepitant HCl trihydrate is an effective non-peptide neurokinin-1 receptor antagonist, suppresses neurogenic dural inflammation, and may have a role in migraine therapy.
T70248	4991W93
	4991W93 is a 5HT(1B/1D) receptor partial agonist, inhibiting electrically induced plasma extravasation, blocking neurogenic plasma protein extravasation, inhibiting release of calcitonin gene-related peptide.
T28516	ReN-1869	NNC-05-1869,NNC 05-1869,NNC-051869,ReN 1869
	ReN-1869 is a histamine H1 receptor antagonist. ReN 1869 is active against inflammation and neurogenic pain. ReN-1869 produces potent and selective antinociceptive effects on dorsal horn neurons after inflammation and ne...