localization — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22062	CCG-100602		Rho , Ras
	CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).		Rho , Ras
T11282	FGTI-2734		Transferase
	FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localizat...		Transferase
T31408	DFHBI-1T	DFHBI1T,DF-HBI-1T,DF HBI 1T,DFHBI 1T
	DFHBI-1T is an RNA aptamer-activated fluorescent probe that transmits through cell membranes.DFHBI-1T can be used for dynamic localization imaging of RNA in living cells.
T26078	Rhodblock 6	Rhodblock6,Rhodblock-6	ROCK
	Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity.		ROCK
T2856	(-)-Epicatechin	L-Epicatechin,Epicatechin,(-)-Epicatechol	Ferroptosis , COX , Endogenous Metabolite
	(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.		Ferroptosis , COX , Endogenous Metabolite
T61355	APX2039	APX-2039,APX 2039	Antifungal
	APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent an...		Antifungal
T9782	Cytochrome C		Others
	Cytochrome C, a protein that belongs to class 1 of the c-type cytochrome family, exerts different functions depending on its cellular localization and the conditions in which it operates.		Others
TP1653L	SV40 T-Ag-derived NLS peptide acetate	SV40 T-Ag-derived NLS peptide acetate(105425-98-7 free base)	Others
	SV40 T-Ag-derived NLS peptide acetate (SV40 T-Ag-derived NLS peptide acetate) is a nuclear localization signal peptide. The DNA labeled with this peptide can be effectively transferred to the nucleus.		Others
T19229	Catalase		Others
	Catalase is an essential enzyme in the metabolism of H2O2 and reactive oxygen species (ROS). The expression and localization of Catalase are markedly altered in tumors.		Others
T40130	Nur77 modulator 1	Nur77 modulator 1	Others
	Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell ...		Others
T27612	INI-43	INI 43,INI43	Others
	INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpn...		Others
T69141	NSC1008
	NSC1008 is an inhibitor of the Ras Converting Enzyme 1 (Rce1) protease that disrupts Ras membrane localization in human cells.
T16941	Stauprimide		Others
	Stauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which causes down-regulation of MYC transcription.		Others
T26342	YH16899	YH-16899,YH 16899,BC-K-YH16899
	YH16899 is a KRS-67LR interaction inhibitor by directly blocking the association between KRS and 67LR, suppressing the dynamic movement of the N-terminal extension of KRS and reducing membrane localization of KRS.
T78448	TPPS		Others
	Tetraphenylporphine sulfonate (TPPS) serves as a non-cytotoxic probe suitable for tumor localization detection [1].		Others
TP1653	SV40 T-Ag-derived NLS peptide
	This peptide, a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus.
T36959	BODIPY 558/568 C12	Red C12
	BODIPY 558/568 C12 is a fatty acid-conjugated fluorescent probe for lipid droplets. [1] [2] It displays excitation/emission maxima of 558/568 nm, respectively, and has been used to monitor the localization and dynamics ...
T11282L	FGTI-2734 mesylate (1247018-19-4 free base)	FGTI-2734 mesylate	Others
	FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates ...		Others
T39936	HM Janelia Fluor® 526, SE	HM-JF526 NHS
	HM Janelia Fluor 526, SE (HM-JF526 NHS) is a derivative of hydroxymethyl JF526 (HM-JF526). SMLM (single-molecule localization microscopy) imaging in standard phosphate-buffered saline (pH 7.4) revealed that the HM-JF526 ...
TP1520	Hepatitis B Virus Core (128-140)	Hepatitis B Virus Core 128-140
	The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during t...