insulinotropic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T83710	Gastric Inhibitory Peptide (22-51) (human) TFA	GIP (22-51),Glucose-dependent Insulinotropic Peptide (22-51)
	Gastric inhibitory peptide (GIP) (22-51), a pro-atherogenic peptide comprised of 30 amino acids from the residues 22-51 of its precursor protein proGIP, is present in human plasma. It activates the degradation of IκB-α a...
T83694	Gastric Inhibitory Peptide (1-42) (porcine) TFA	GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
	Gastric inhibitory peptide (GIP) (1-42), an endogenous incretin hormone comprising 42 amino acids, promotes insulin secretion. Expressed in the intestinal neuroendocrine K cells and submandibular gland, it enters circula...
T83696	Gastric Inhibitory Peptide 1 (3-42) (human) TFA	Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42)
	Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmo...
T6587	Mitiglinide Calcium	KAD-1229,S21403	ATPase , Potassium Channel
	Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.		ATPase , Potassium Channel
T1530	Mitiglinide calcium hydrate	KAD-1229 calcium hydrate,Mitiglinide calcium,S-21403 calcium hydrate	Potassium Channel
	Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic ...		Potassium Channel
T83972	NOX-6-18	GPR132 antagonist 1,GPR132-B-160	GPR
	NOX-6-18 (GPR132-B-160) is a highly potent and selective GPR132 antagonist with insulinotropic activity that modulates macrophage reprogramming in pancreatic islets and reduces weight gain.		GPR
T7448	4-Hydroxyisoleucine	4-Hydroxy-L-isoleucine	Others
	4-Hydroxyisoleucine (4-Hydroxy-L-isoleucine) has antidepressant-like, antidyslipidemic, and antihyperglycemic effects. It displays an insulinotropic activity.		Others
T37588L	GIP (1-30) amide, porcine acetate		IGF-1R
	GIP (1-30) amide, porcine acetate is an agonist of fully glucose-dependent insulinotropic polypeptide (GIP) receptor. GIP (1-30) amide, porcine acetate can weakly inhibit gastric acid secretion and strongly stimulate ins...		IGF-1R
TP2252	GLP-1 (9-36) amide		Glucagon Receptor
	antagonist at the human GLP-1 receptor		Glucagon Receptor
T76279	Retatrutide	LY3437943	Glucagon Receptor
	Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide ...		Glucagon Receptor
T2P2919	(2S,3R,4S)-4-Hydroxyisoleucine	(4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine	PI3K
	(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr...		PI3K
TP1566	GIP (1-30) amide (Human) (TFA)
	GIP (1-30) amide (Human) TFA is a glucose-dependent insulinotropic polypeptide fragment. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates insulin secretion and reduces postprandia...
T37588	GIP (1-30) amide, porcine
	This GIP fragment has potent insulinotropic activity in the isolated, perfused rat pancreas but greatly reduced somatostatinotropic activity in the isolated perfused rat stomach. The site responsible for insulinotropic a...
TP1110	Tirzepatide hydrochloride	LY3298176 hydrochloride
	Tirzepatide hydrochloride (LY3298176 hydrochloride) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.
T82316	GIP, rat TFA
	GIP, rat TFA (glucose-dependent insulinotropic polypeptide), a 42-amino acid peptide secreted by K cells in the duodenum and jejunum, promotes insulin release from pancreatic beta cells, supports beta cell proliferation,...
T76310	Acetyl Gastric Inhibitory Peptide (human)
	Acetyl Gastric Inhibitory Peptide (human), a fatty acid-derivatized analog of glucose-dependent insulinotropic polypeptide, exhibits enhanced antihyperglycemic and insulinotropic characteristics. This compound is utilize...
T61414	DPP-4 inhibitor 3
	Compound 5a, also known as DPP-4 inhibitor 3, is a powerful dipeptidyl peptidase IV (DPP-IV) inhibitor, demonstrating an IC50 value of 0.75 nM. It exhibits outstanding antioxidant and insulinotropic activity [1].
T78543	Acetyl Gastric Inhibitory Peptide (human) TFA	Human N-acetyl GIP TFA
	Acetyl Gastric Inhibitory Peptide (human) TFA, a fatty acid-derivatized analog of the glucose-dependent insulinotropic polypeptide, exhibits enhanced antihyperglycemic and insulinotropic properties. It is utilized in the...
T37601	GIP (1-30) amide, porcine TFA
	GIP (1-30) amide, porcine TFA is a high-affinity full agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor, having a similar potency as the native GIP(1-42) [1]. Furthermore, GIP (1-30) amide, porci...
T37589L	GIP (3-42), human acetate	GIP (3-42), human acetate(1802086-25-4 Free base)	IGF-1R
	GIP (3-42), human acetate is an antagonist of a glucose-dependent insulinotropic polypeptide (GIP) receptor and regulates insulin secretion and GIP metabolism in vivo.		IGF-1R