immune-modulating — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8689	Chloroquine	CQ	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als...
T0194	Chloroquine phosphate	Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T7544	Fucoidan		Others
	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.		Others
T15705	Laminaran	β-1,3-Glucan
	Laminaran is a β-1,3-glucan isolated from brown algae, often serving as a typical ligand for Dectin-1. It possesses anti-cancer, immune-modulating, and radiation-protective properties. Laminaran can be catalyzed by gluca...
T4S1469	Cucurbitacin IIb		Apoptosis , Others
	1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...		Apoptosis , Others
T26582	AIM-102
	AIM-102, a nonsteroidal, immune modulating, anti-inflammatory drug, is used potentially for the treatment of allergic asthma.
T7009	Soyacerebroside II		IL Receptor , Calcium Channel
	Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral...		IL Receptor , Calcium Channel
T82593	Debotansine
	"Debotansine, an immunomodulator and antineoplastic [1], is a chemical compound with therapeutic applications in modulating the immune system and combating cancer."
T81114	Spns2-IN-1		LPL Receptor
	Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune response [1].		LPL Receptor
T74651	L-Inosine
	L-Inosine, the L-configuration of Inosine, is an endogenous purine nucleoside derived from adenosine catabolism. It exhibits anti-inflammatory, antinociceptive (pain-relieving), immunomodulatory (immune system-modulating...
TN3741	Cyclocurcumin		TNF , ROS
	Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It m...		TNF , ROS
T80089	HCV-1 e2 Protein (554-569) (TFA)
	HCV-1 e2 Protein (554-569) TFA, an antigenic segment of the hepatitis C virus envelope 2 (e2) protein, encompasses a potential N-glycosylation site implicated in modulating immune recognition of e2 [1].
T76748	Foralumab
	Foralumab (NI-0401) is a powerful, orally administered humanized monoclonal antibody that specifically targets the CD3 receptor. By modulating immune responses in NSG mice reconstituted with human hematopoietic stem cell...
T74910	ODN 24888
	ODN 24888, a guanine-modified inhibitory oligonucleotide (INH-ODN), effectively inhibits TLR7/TLR9-mediated signaling, reducing IFN-α levels and NF-κB activation, and suppressing IL-6 release. This compound plays a role ...
T76022	Chemerin-9 (149-157) (TFA)
	Chemerin-9 (149-157) TFA is a potent CMKLR1 (chemokine-like receptor 1) agonist with anti-inflammatory properties. It activates phosphorylation of Akt and ERK and induces ROS production, beneficially modulating immune re...
T37644	Bengamide B
	Potent inhibitor of NF-κB activation (IC50 = 85 nM); decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cell...