hemorrhagic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38238	2'-Deoxy-2'-fluorocytidine		Nucleoside Antimetabolite/Analog , Influenza Virus
	2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o...		Nucleoside Antimetabolite/Analog , Influenza Virus
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease
	FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective ...
T1414	Sodium 2-mercaptoethanesulfonate	Mitexan,Uromitexan,Mesna,Mesnum,Mesnex	Others
	Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.		Others
T5963	Menadione bisulfite sodium	Sodium menadione bisulfite,Menadione sodium bisulfite,Vitamin K3 sodium bisulfite	Others
	Menadione bisulfite sodium (Vitamin K3 sodium bisulfite) is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement.		Others
T12001	Menaquinone-7	Vitamin MK-7,Vitamin K2-7,Vitamin K2(35)	Others
	Menaquinone-7 (Vitamin K2(35)) is a vitamin K2 analog, is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 (Vitamin K2(35)) is identified as the most bioactive cofactor for the carboxylation reaction ...		Others
T21967	MEG hemisulfate	Mercaptoethylguanidine hemisulfate	NOS
	MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS i...		NOS
T31564	Dopamine, lys-pro-amide-
	Dopamine, lys-pro-amide- is equieffective to dopamine as to its protective activity against hemorrhagic shock.
T77140	Ralpancizumab
	Ralpancizumab, a selective PCSK9 inhibitor, shows potential for use in hemorrhagic stroke [1].
T27590	IHVR-11029	IHVR 11029
	IHVR-11029 is a potent inhibitor of ER α-glucosidase. IHVR-11029 is active against multiple hemorrhagic fever viruses and efficiently disrupts the morphogenesis of a broad spectrum of enveloped viruses.
T15554	IHVR-19029		Others
	IHVR-19029 is an effective endoplasmic reticulum (ER) α-glucosidases I and II inhibitor (IC50: 0.48 μM for ER a-glucosidase I). IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as ...		Others
T26589	Albifylline
	Albifylline is a xanthine derivates with anti-asthmatic activity. Albifylline may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. Alb...
T27050	CM-10-18	CM-1018
	CM-10-18 is a potent inhibitor of ER α-glucosidase. CM-10-18 demonstrated superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever. CM-10-18 efficiently prote...
T80341	Seabream hepcidin
	Seabream hepcidin, an antimicrobial peptide, exhibits antibacterial (V. anguillarum), antifungal (S. cerevisiae), and antiviral activities against hemorrhagic septicemia virus [1].
T70838	RO27-3225 TFA
	RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225...
T11281	FGI-106		Others
	FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. ...		Others
T77166	Rovelizumab
	Rovelizumab, a humanized monoclonal leukointegrin antibody, targets CD11/CD18 cell adhesion proteins. It has potential applications in the research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI...
T80154	TAT-CIRP
	TAT-CIRP, a trans-activating (Tat) cold-inducible RNA-binding protein-derived peptide, functions as an inhibitor of myeloid differentiation protein 2 (MD2). It has demonstrated significant neuroprotective effects against...
T78586	Ac-IETD-CHO		Apoptosis
	Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. Furthermore, this compound hampers cell death induced by cy...		Apoptosis
TP2184	Matrix protein (3-15) [Zaire ebolavirus]		Others
	matrix protein (3-15) [Zaire ebolavirus] is a peptide of the structural proteins linking the viral envelope with the zaire ebolavirus core. Ebola virus (EBOV) is a member of the family Filoviridae in the order Mononegavi...		Others
T75847	PG-931 TFA
	PG-931 TFA, a potent and selective agonist of the melanocortin 4 (MC4) receptor (IC50=0.58 nM) compared to the hMC3R (IC50=55 nM) and hMC5R (IC50=2.4 nM), is an analog of SHU 9119. This compound has demonstrated efficacy...