gluconeogenesis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN7038	Regaloside H		Others
	Regaloside H, a glyceryl phenylpropionate glycoside, is a gluconeogenesis inhibitor.		Others
T22891	KL001	KL 001,KL-001	Others
	KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced glu...		Others
T1116	Biotin	Vitamin B7,D-Biotin,Vitamin H
	Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
T15389L	Glucagon (1-29), bovine, human, porcine hydrochloride	Porcine glucagon hydrochloride,Glucagon hydrochloride	Glucocorticoid Receptor , Glucagon Receptor
	Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon (1-29), bovine, human, porcine hydrochloride(Po...		Glucocorticoid Receptor , Glucagon Receptor
T5045	GSK4112	1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452	Autophagy
	GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.		Autophagy
T64345	4-(Dimethylamino)phenol		Others
	4-(Dimethylamino)phenol enhances extracellular lactate dehydrogenase (LDH) levels without significant effects on gluconeogenesis. Only when the membrane becomes permeable to LDH does 4-(Dimethylamino)phenol reduce ATP co...		Others
T1614	Hydrocortisone	Cortisol	Glucocorticoid Receptor , Endogenous Metabolite
	Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilizatio...		Glucocorticoid Receptor , Endogenous Metabolite
T37984	D-Fructose-1,6-bisphosphate sodium salt hydrate		Others
	D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by ph...		Others
T37185	D-(-)-3-Phosphoglyceric acid disodium	3-Phospho-D-glyceric acid disodium	Others
	D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine...		Others
T5248	(R)-3-Hydroxybutanoic acid		Others , Endogenous Metabolite
	3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. B...		Others , Endogenous Metabolite
T3976	Cytosporone B	Csn-B,Dothiorelone G	Others
	Cytosporone B (Dothiorelone G) is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene...		Others
T20028	Janumet	Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate
	Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator.
T15389	Glucagon (1-29), bovine, human, porcine	Porcine glucagon,Glucagon	Others
	Glucagon is a peptide hormone, produced by pancreatic α-cells. Glucagon reduces the activity of HNF-4. Glucagon stimulates gluconeogenesis. Glucagon enhances HNF4α phosphorylation.		Others
T25572	Ketohypoglycin	Methylenecyclopropylpyruvate
	Ketohypoglycin has been utilized to study the inhibition of gluconeogenesis in isolated rat liver cells.
T69481	Clanobutin
	Clanobutin inhibits gluconeogenesis and acts as a choleretic and digestion-stimulating agent.
T10786	Charantin		GSK-3
	Charantin is a steroidal saponin isolated from Momordica charantia. It increases the release of insulin and slowing down gluconeogenesis. Charantin can inhibit GSK-3.		GSK-3
T70141	MDK80908
	MDK80908, also known as PPARalpha/gamma agonist N15, is a dual PPARα/γ agonist, ameliorating insulin resistance and gluconeogenesis in vivo and vitro. MDK80908 has CAS#1821380-90-8.
T35265	YM-440	YM440,YM 440
	YM-440 is a novel hypoglycemic agent, an insulin sensitizer, that may be used for the treatment of type 2 diabetes mellitus by reducing glucose 6-phosphatase activity in obese Zucker rats and inhibiting liver glucose out...
T36927	Hydrocortisone phosphate
	Hydrocortisone phosphate is the pharmaceutical term for cortisol, which is a steroid hormone, in the glucocorticoid class of hormones, increases blood sugar through gluconeogenesis, to suppress the immune system, and to ...
T37783	2,5-Anhydro-D-mannitol
	2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, ...