farnesyl — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8028	Farnesyl acetate	Farnesyl Acetate (mixture of isomers)	Others
	Farnesyl acetate (Farnesyl Acetate (mixture of isomers)) is a flavouring compound identified in foods such as blueberries.		Others
T78081	Farnesyl Pyrophosphate ammonium	Farnesyl diphosphate ammonium
	Farnesyl Pyrophosphate Ammonium Salt, a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, functions as a TRPM2 (TRP Channel) agonist, facilitating the opening of TRPM2 channels for ion influx. It serves as ...
T37775	Farnesyl Pyrophosphate (ammonium salt)
	Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FP...
T10363	Arazine	N-Acetyl-S-farnesyl-L-cysteine	Others
	Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and G...		Others
T35764	S-Farnesyl Thioacetic Acid
	S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine which behaves as a competitive inhibitor of isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). It can ...
T35433	α-hydroxy Farnesyl Phosphonic Acid
	α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phos...
T6163	Salirasib	Farnesyl Thiosalicylic Acid,S-Farnesylthiosalicylic acid,FTS	Autophagy , Ras
	Salirasib (Farnesyl Thiosalicylic Acid)(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity.		Autophagy , Ras
TN7168	Farnesylacetone	(5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one,Farnesyl acetone,E,E-farnesylacetone	Others
	Farnesylacetone ((5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one) is a marine derived natural products found in Sargassum micracanthum.		Others
T73755	Farnesyl pyrophosphate
	Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, acts as a metabolic intermediary. It serves as a TRPM2 (TRP Channel) agonist, facilitating the opening of T...
T11282	FGTI-2734		Transferase
	FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localizat...		Transferase
TN6512	Tectol		Transferase , Parasite
	Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...		Transferase , Parasite
T2678	LB42708		Transferase
	LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).		Transferase
T6302	Lonafarnib	Sarasar,Sch66336	Raf , Transferase , Autophagy , Ras
	Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).		Raf , Transferase , Autophagy , Ras
TQ0165	Arglabin	(+)-Arglabin	NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
	Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.		NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
T3182	L-778123 hydrochloride	L 778123	Telomerase , Transferase
	The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.		Telomerase , Transferase
T2700	FTI-277 hydrochloride	FTI 277 HCl	Apoptosis , Transferase , Ras
	FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.		Apoptosis , Transferase , Ras
T38050	CP-609754		Transferase
	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...		Transferase
T6271	Tipifarnib	R115777,Zarnestra,IND 58359	Transferase
	Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnes...		Transferase
T17102	Tipifarnib (S enantiomer)	Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer	Transferase
	Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).		Transferase
T8249	Hexahydrofarnesyl acetone	Phytone	Others , Antibacterial
	Hexahydrofarnesyl acetone (Phytone) enhanced both the sticky materials production and cell growth, plays some role in the increase of sticky materials and cell growth.		Others , Antibacterial