facilitate — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7460	α-Cyano-4-hydroxycinnamic acid	α-Cyano-4-hydroxycinnamic acid(α-CHCA)	Monocarboxylate transporter
	α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate transport in rat heart mitochondria (IC50 : 1.5 μM).		Monocarboxylate transporter
T3931	Isobavachin		Others
	Isobavachin can facilitate mouse ES cells differentiating into neuronal cells.		Others
TN1529	Coumarin 6	Coumarin VI	Others
	Coumarin 6 (Coumarin VI) is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.		Others
T0156	Rocuronium bromide	ORG 9426,ORG 9426 (Bromide)	AChR
	Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeleta...		AChR
T60485	DIF-3
	DIF-3 is a chemical compound that acts by activating GSK-3β to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/β-catenin signal...
T19529	Proteinase		Others
	Proteinases are enzymes that catalyse the breakdown of proteins. Proteinases are involved in many biological functions, including the digestion of ingested proteins, the breakdown of old proteins, and cell signalling. Th...		Others
T6S0525	Farrerol		ERK , p38 MAPK , Akt
	1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....		ERK , p38 MAPK , Akt
T17975	Fmoc-NH-pentanoic acid-NHS-SO3Na		Others
	Fmoc-NH-pentanoic acid-NHS-SO3Na is a PROTAC linker molecule derived from an alkyl chain. It possesses the ability to facilitate the synthesis of PROTACs[1].		Others
T25637	Laudexium methylsulfate	Laudexium,Laudolissin methosulphate
	Laudexium methylsulfate is a neuromuscular blocking drug or skeletal muscle relaxant. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during ...
T18446	N-Methyl-N'-(hydroxy-PEG2)-Cy5		Others
	N-Methyl-N'-(hydroxy-PEG2)-Cy5 is a PEG-based linker utilized for the synthesis of PROTACs. It serves as a chemical compound with the ability to facilitate the formation of PROTACs[1].		Others
T25636	Laudexium	Laudexium ion,Laudexium cation
	Laudexium is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubatio...
T14101	Acid-PEG3-C2-Boc		Others
	Acid-PEG3-C2-Boc is a compound used as a linker in the synthesis of PROTACs to facilitate the degradation of EGFR and the inhibition of mTOR[1][2]. It is classified as a PEG- and alkyl/ether-based PROTAC linker.		Others
T17811	DBCO-SS-aldehyde		Others
	DBCO-SS-aldehyde is an ADC linker employed for ADC synthesis[1]. This cleavable linker is designed to facilitate the conjugation of antibodies and drugs, resulting in antibody-drug conjugates (ADCs).		Others
T80972	TNH	TMP-NVOC linker-Halo
	TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].
T81961	Lacto-N-difucohexaose I	LDFH I
	Lacto-N-difucohexaose I (LNDFH I), a connecting agent, may facilitate the attachment of Lewis b sugar chain-bearing oligosaccharides to water-insoluble polysaccharides [1].
T39642	Thalidomide-O-C3-acid	Thalidomide-O-C3-acid
	Thalidomide-O-C3-acid is a chemically derived conjugate that combines a cereblon ligand based on Thalidomide and a linker commonly employed in PROTAC technology. This synthesized E3 ligase ligand-linker conjugate serves ...
T17943	FAK ligand-Linker Conjugate 1		Others
	FAK ligand-Linker Conjugate 1 is a chemical compound designed to facilitate PROTAC-mediated protein degradation. This compound consists of a ligand specifically targeting FAK and a PROTAC linker module, which acts as a r...		Others
T68206	Arbortristoside A
	Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and ...
T61090	CD73-IN-8
	CD73-IN-8, a potent CD73 inhibitor, prevents the catalytic activity of CD73, an enzyme responsible for converting extracellular 5'-phosphate adenosine (5'-AMP) to adenosine. Adenosine, once produced, can induce immunosup...
T75379	Biotin-16-UTP
	Biotin-16-UTP serves as an efficient substrate for RNA polymerase, capable of substituting UTP in vitro transcription reactions to facilitate RNA labeling [1].