electrophysiological — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8357	SB-200646		5-HT Receptor
	SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor		5-HT Receptor
T2067	NS11394	NS 11394	GABA Receptor
	NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > α(1) at GABA(A) alpha subunit-containing receptors.		GABA Receptor
T24885L	Tiaspirone hydrochloride	BMY-13859 hydrochloride,Tiaspirone hydrochloride（87691-91-6 Free base)	Dopamine Receptor , 5-HT Receptor
	Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 ...		Dopamine Receptor , 5-HT Receptor
T61025	GSK-1482160		P2X Receptor
	GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so G...		P2X Receptor
T70540	Pinokalant	LOE-908	SARS-CoV , TRP/TRPV Channel
	Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabolic and electrophysiological status of the ischem...		SARS-CoV , TRP/TRPV Channel
T0866	Propafenone	Rythmol,Propafenonum	Potassium Channel , MRP , Sodium Channel
	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....		Potassium Channel , MRP , Sodium Channel
T68399	Pitrazepin
	Pitrazepin is a new GABAA receptor antagonist reported to antagonize electrophysiological effects of GABA
T68185	U 66985
	U 66985 is a Platelet-activating factor (PAF) receptor antagonist that inhibit the electrophysiological effects of PAF.
T35082	VU6010608	VU-6010608,VU 6010608
	VU6010608 is an effective mGlu7 NAM with excellent CNS permeability and is powerful in electrophysiological studies in blocking long-term enhancement of high-frequency stimuli.
T32030	GYKI-16638 HCl	GYKI 16,638,GYKI16,638,GYKI-16638,GYKI-16,638,GYKI16638,GYKI 16638
	GYKI-16638 is a novel antiarrhythmic agent that demonstrates combined class IB and class III antiarrhythmic properties in human ventricular muscles, similar to the electrophysiological findings after chronic amiodarone t...
T26751	BBR 2160	BBR-2160,BBR2160
	BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine. BBR 2160 has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize th...
T22423	SB-200646A		5-HT Receptor
	SB-200646A is an orally active, selective antagonist of 5-HT2B/2C over 5-HT2A receptor with pKi of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646A exerts anxiolytic and electrophysiological pro...		5-HT Receptor
TP2078	AC 253
	Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death ...
T20636	Latrunculin B	LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644	Antifungal
	Latrunculin B, an alkaloid from the Red Sea sponge, is an actin polymerization inhibitor with antifungal and antiprotozoal activity.Latrunculin B modulates the electrophysiological characteristics of the pulmonary veins ...		Antifungal
T71000	RO-5328673
	RO-5328673 is a dual NK2/NK3 antagonist. O5328673. [(3)H]RO5328673 bound to a single saturable site on hNK2, hNK3 and gpNK3 with high-affinity. RO5328673 acted as an insurmountable antagonist at both human and guinea-pig...