dermatophytes — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1497	Liranaftate	Piritetrate,M-732	Antifungal
	Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...		Antifungal
T1543	Naftifine hydrochloride	Naftifungin,Naftifine HCl,Naftin,Exoderil	Hedgehog/Smoothened , Antibiotic , Antifungal
	Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its...		Hedgehog/Smoothened , Antibiotic , Antifungal
T25982	Pramiconazole	R-126638,R126638,R 126638,Azoline	Antifungal
	Pramiconazole (R126638) is an orally available antifungal compound.Pramiconazole is a candidate for the treatment of dermatophytes and cutaneous yeast infections in seborrheic dermatitis.		Antifungal
T16033	ME1111		Others , Antifungal
	ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes. Notably proficient in penetrating human nails, it is utilized in onychomycosis research.		Others , Antifungal
T8167	Medicagenic acid	Castanogenin	Antibacterial
	Medicagenic acid (Castanogenin), isolated from the roots of Herniaria glabra L, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes.		Antibacterial
T1411	Terbinafine hydrochloride	KWD 2019,Terbinafine HCl,TDT 067 hydrochloride	Antibacterial , Antibiotic , Antifungal
	Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.		Antibacterial , Antibiotic , Antifungal
T7026L	Kukoamine B mesylate		Antioxidant
	Kukoamine B mesylate is a novel cationic alkaloid derived from dermatophytes with antioxidant activity, inhibits LPS internalization in Kupffer and RAW 264.7 cells, and can be used to study acute inflammation and diabete...		Antioxidant
T1438	Butoconazole nitrate	RS 35887	Estrogen/progestogen Receptor , Antifungal
	Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversi...		Estrogen/progestogen Receptor , Antifungal
TN4811	Plumieride
	Plumieride has plant growth inhibiting properties, it shows strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. Plumieride also has antioxidant , and immunomodulatory activ...
T28476	Pyrroxamycin	LL-F42248-alpha,Dioxapyrrolomycin,AL-R2081
	Pyrroxamycin is a new antibiotic. Pyrroxamycin was isolated from the culture broth of Streptomyces sp. S46506. Pyrroxamycin is active against Gram-positive bacteria and dermatophytes.
T68998	Parconazole Free Base
	Parconazole Free Base is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of acti...
T69369	Cladosporin
	Cladosporin, a metabolite derived from the mycelium of Cladosporium cladosporioides, effectively halts the growth of several dermatophytes on agar medium when applied at a concentration of 75 µg/mL, demonstrating its pot...
T35857	Actinopyrone A
	Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities. It has selective and potent antimicrobial activity against H. pylori (MIC = 0.1 ng/mL) with no activity against other Gram-negative b...
T27300	Olorofim	Olorofim,F901318,F-901318
	Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pa...