deaminase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19179	Adenosine deaminase		Others
	Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of 2'-deoxyadenosine and adenosine to 2'-deoxyinosine and inosine, respectively.		Others
T60800	Deaminase inhibitor-1
	Deaminase inhibitor-1 is an APOBEC3G DNA Deaminase inhibitor with an IC 50 value of 18.9 μM [1].
T9111	8-Azaadenosine		Adenosine deaminase
	8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.		Adenosine deaminase
TN1736	Hibifolin		Adenosine deaminase
	Hibifolin is a flavonol glycoside natural product,is a potential inhibitor of adenosine deaminase (Ki of 49.92 μM). Hibifolin protects neurons against beta-amyloid-induced neurotoxicity.		Adenosine deaminase
T4006	Pentostatin	Nipent,CI-825,Covidarabine,Deoxycoformycin	Adenosine deaminase , Adenosine Receptor
	Pentostatin (CI-825) is an extremely effective and irreversible inhibitor of adenosine deaminase (Ki: 2.5 pM).		Adenosine deaminase , Adenosine Receptor
T2558	Cladribine	2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA	Apoptosis , Adenosine deaminase
	Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.		Apoptosis , Adenosine deaminase
T2169	Zebularine	NSC309132,4-Deoxyuridine	DNA Methyltransferase , Autophagy
	Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cytidine deaminase (Ki: 2...		DNA Methyltransferase , Autophagy
T26972	Cedazuridine	(4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine	DNA Methyltransferase
	Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.		DNA Methyltransferase
T13482	2'-O-Methyladenosine		Endogenous Metabolite
	2'-O-Methyladenosine, a methylated adenine residue is found in the urine of normals and adenosine deaminase deficient patients. It shows unique hypotensive activities.		Endogenous Metabolite
T6987	β-Chloro-L-alanine	3-Chloro-L-alanine,L-β-Chloroalanine	Antibacterial
	β-Chloro-L-alanine (L-β-Chloroalanine) is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.		Antibacterial
TNU0060	3’-O-Methyladenosine		Antiviral , Adenosine deaminase
	3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-Methyladenosine inhibits adenosine deaminase type VII with a Ki va...		Antiviral , Adenosine deaminase
T50029	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine	2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine	Others
	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine (2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine) is a heterocyclic compound. It inhibits monoamine oxidase, resulting in elevated monoamine levels in the body. It can...		Others
T0665	Xanthine	2,6-Dihydroxypurine,Isoxanthine	Endogenous Metabolite , Adenosine Receptor
	Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in...		Endogenous Metabolite , Adenosine Receptor
T4901	5'-Guanylic acid disodium salt	Guanosine 5'-monophosphate disodium salt,GMP-5	Others , Endogenous Metabolite
	5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy...		Others , Endogenous Metabolite
T19146	5,6-Dihydrouridine		Endogenous Metabolite
	5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.		Endogenous Metabolite
T23634	Adecypenol	OM-3223,OM3223,OM 3223,Antibiotic OM 3223
	Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase.
T27384	FR-234938	FR 234938
	FR-234938 is a non-nucleoside adenosine deaminase inhibitor with anti-inflammatory activity.
T23905	Coformycin	NSC 277817
	Coformycin is a ribonucleoside antibiotic synergist and adenosine deaminase inhibitor.
T70255	Elapegademase
	Elapegademase is an Adenosine Deaminase Inhibitor
T27383	FR-221647
	FR-221647 is a non-nucleoside adenosine deaminase inhibitor, it has moderate activity and good pharmacokinetics compared with the known inhibitors EHNA and pentostatin.